Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.77 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | NQO2 | P16083 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382094 | 0.94 | MTNR1A (0.72) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL3264594 | 0.93 | MTNR1A (0.71) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL3228696 | 0.93 | MTNR1A (0.71) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL3384642 | 0.91 | MTNR1A (0.64) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL3235282 | 0.90 | MTNR1A (0.69) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL3384994 | 0.88 | MAPT (0.68) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL3227925 | 0.88 | MTNR1A (0.69) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL8946916 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL31543713 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BMAPTKMT2AMEN1 | |
| SCHEMBL18222560 | 0.85 | MTNR1A (0.78) | MTNR1AMTNR1BMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012396-A1 | 5,6 SUBSTITUTED BENZAMIDE DERIVATIVES AS MODULATORS OF THE EP<SB>2 </SB>RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| WO-2010012396-A1 | 5,6 SUBSTITUTED BENZAMIDE DERIVATIVES AS MODULATORS OF THE EP<SB>2 </SB>RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | disclosed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |