Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.72 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | NQO2 | P16083 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227065 | 0.94 | MTNR1A (0.77) | MTNR1AMTNR1BPOLBALDH1A1KDM4E | |
| SCHEMBL3228696 | 0.90 | MTNR1A (0.71) | MTNR1AMTNR1BPOLBMAPTKMT2A | |
| SCHEMBL3264594 | 0.90 | MTNR1A (0.71) | MTNR1AMTNR1BPOLBALDH1A1MAPT | |
| SCHEMBL3384980 | 0.88 | MEN1 (0.61) | MTNR1AMTNR1BPOLBMAPTKMT2A | |
| SCHEMBL3235282 | 0.87 | MTNR1A (0.69) | MTNR1AMTNR1BPOLBALDH1A1KDM4E | |
| SCHEMBL3384642 | 0.85 | MTNR1A (0.64) | MTNR1AMTNR1BPOLBMAPTKMT2A | |
| SCHEMBL3227925 | 0.85 | MTNR1A (0.69) | MTNR1AMTNR1BPOLBALDH1A1KDM4E | |
| SCHEMBL31543713 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BPOLBALDH1A1KDM4E | |
| SCHEMBL8946916 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BPOLBALDH1A1KDM4E | |
| SCHEMBL3384994 | 0.83 | MAPT (0.68) | MTNR1AMTNR1BPOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |