Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584337 | 0.83 | TSHR (0.45) | CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL1453183 | 0.78 | TSHR (0.36) | ALDH1A1TLR8 | |
| SCHEMBL3848205 | 0.76 | RECQL (0.36) | ALDH1A1 | |
| SCHEMBL11202895 | 0.76 | TSHR (0.39) | ALDH1A1HSD17B10KDM4EPOLBCYP3A4 | |
| SCHEMBL7505763 | 0.76 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2TLR8TDP1L3MBTL1 | |
| SCHEMBL31558464 | 0.76 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2TLR8TDP1L3MBTL1 | |
| SCHEMBL1451955 | 0.73 | GABRA1 (0.36) | CYP1A2CYP3A4PTGS1 | |
| SCHEMBL5952904 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL1256860 | 0.73 | CA1 (0.43) | CYP1A2CYP2C9CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL1453289 | 0.73 | HTR1B (0.40) | ALDH1A1KDM4ESMN1; SMN2TDP1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110312007-A1 | Detection of Histone Deacetylase Inhibition | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2011-12-22 | — | — | US | disclosed |
| US-20100062465-A1 | Detection of Histone Deacetylase Inhibition | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-03-11 | — | — | US | disclosed |
| WO-2007124435-A2 | DETECTION OF HISTONE DEACETYLASE INHIBITION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312007-A1 | Detection of Histone Deacetylase Inhibition | HDAC1, HDAC3, HDAC7 | CYP1A2 4431/4885CYP2C9 4599/4885CYP2C19 4520/4885 |
| US-20100062465-A1 | Detection of Histone Deacetylase Inhibition | HDAC1, HDAC3, HDAC11 | CYP1A2 4436/4885CYP2C9 4605/4885CYP2C19 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.