Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL27660704 | 0.96 | TSHR (0.40) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL8639212 | 0.89 | TSHR (0.47) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL28427180 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL7458807 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL25701964 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL1557285 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL8992346 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL10716954 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL6246201 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL10842205 | 0.86 | TSHR (0.53) | TSHRLMNATHRBALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058265-B2 | 1a-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-11-15 | — | — | US | claimed |
| US-7736634-B2 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2010-06-15 | — | — | US | claimed |
| US-20090281340-A1 | 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | claimed |
| US-7595370-B2 | Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems | PPG B.V. (NL) | 2009-09-29 | — | — | US | claimed |
| EP-2010483-A2 | 1.ALPHA.-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND USE THEREOF | Wisconsin Alumni Research Foundation (US) | 2009-01-07 | — | — | EP | claimed |
| US-20070244072-A1 | 1a-Hydroxy-2-(3'-Hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-10-18 | — | — | US | claimed |
| WO-2007117563-A2 | 1.ALPHA.-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-10-18 | — | — | WO | claimed |
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2006-06-29 | — | — | US | claimed |
| EP-1558654-A4 | NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF | FUJIFILM ELECTRONIC MATERIALS (US) | 2006-04-05 | — | — | EP | claimed |
| EP-1558654-A2 | NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF | Fujifilm Electronic Materials USA, Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| US-6916543-B2 | Copolymer, photoresist compositions thereof and deep UV bilayer system thereof | ARCH SPECIALTY CHEMICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |
| EP-1539861-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | Sigmakalon Services B.V. (NL) | 2005-06-15 | — | — | EP | claimed |
| US-20040137362-A1 | Novel copolymer, photoresist compositions thereof and deep UV bilayer system thereof | ARCH SPECIALTY CHEMICALS, INC. | 2004-07-15 | — | — | US | claimed |
| WO-2004040371-A2 | NOVEL COPOLYMER AND PHOTORESIST COMPOSITIONS THEREOF | ARCH SPECIALTY CHEMICALS, INC. (US) | 2004-05-13 | — | — | WO | claimed |
| WO-2004007591-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | SIGMAKALON SERVICES B.V. (NL) | 2004-01-22 | — | — | WO | claimed |
| EP-1380611-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SigmaKalon Group B.V. (NL) | 2004-01-14 | — | — | EP | claimed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| EP-3915995-B1 | PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS | MOMENTIVE PERFORMANCE MAT INC (US) | 2025-11-26 | — | — | EP | disclosed |
| EP-0148128-A2 | Optically active penem compounds | CIBA-GEIGY AG (CH) | 1985-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | C1R, C9, PCBP1 | TSHR 3690/4885LMNA 3271/4885THRB 4122/4885 |
| US-20070244072-A1 | 1a-Hydroxy-2-(3'-Hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | CYP24A1, CYP2R1, VDR | TSHR 1281/4885LMNA 639/4885THRB 355/4885 |
| US-20090281340-A1 | 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF | CYP24A1, CYP2R1, VDR | TSHR 1670/4885LMNA 628/4885THRB 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.