Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451792 | 0.74 | MEN1 (0.59) | HRH4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3227319 | 0.73 | MEN1 (0.50) | HRH4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3450708 | 0.73 | ALDH1A1 (0.58) | HRH4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3233802 | 0.72 | TLR8 (0.71) | HRH4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3473227 | 0.72 | MEN1 (0.66) | HRH4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3220814 | 0.71 | MEN1 (0.59) | HRH4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3237770 | 0.70 | SMN1; SMN2 (0.54) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3229148 | 0.70 | SMN1; SMN2 (0.54) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3228726 | 0.70 | HRH4 (0.57) | HRH4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3233891 | 0.70 | MEN1 (0.54) | MEN1KMT2AL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |