SCHEMBL3227829

SCHEMBL3227829

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nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
PDE4A P27815 1/20 0.40
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
MGAM O43451 3/20 0.36
KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3009609 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL1403818 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL5667760 0.98 LMNA (0.46) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL18585305 0.98 TDP1 (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL4424347 0.98 LMNA (0.46) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL18585898 0.96 LMNA (0.42) LMNAL3MBTL1TDP1PDE4AUSP2
Ammonia Solution, Strong SCHEMBL15994055 0.94 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL17571074 0.86 LMNA (0.33) LMNAL3MBTL1TDP1
SCHEMBL18585575 0.86 LMNA (0.33) LMNAL3MBTL1TDP1
SCHEMBL3748924 0.85 USP2 (0.36) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62215510-A None JP disclosed
JP-8081351-A None JP disclosed
WO-2023160616-A1 A HYDROGEL COMPOSITION FOR PREPARING CUSTOMIZED MASK PACK BASF SE (DE) 2023-08-31 WO disclosed
US-20100062029-A1 Product for the Targeted Release of Active Substances LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2010-03-11 US disclosed
US-20080145388-A1 cosmetic cleaning product for controlling release; two layers define a compartment between them, which contains the active substance and optionally a gas-releasing component; one is impermeable, and one is permeable to the active substance; single use for body care; glove shape LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2008-06-19 US disclosed
US-20060052263-A1 Soap preparation with air bubbles SCS SKIN CARE SYSTEMS GMBH 2006-03-09 US disclosed
CN-1192780-C Therapeutical agent TAKARA SHUZO CO (JP) 2005-03-16 CN disclosed
CN-1355703-A Therapeutical agent TAKARA SHUZO CO (JP) 2002-06-26 CN disclosed
EP-1175907-A1 REMEDIES Takara Shuzo Co, Ltd. (JP) 2002-01-30 EP disclosed
WO-1999007339-A1 COMPOSITIONS FOR VISUALLY IMPROVING SKIN THE PROCTER & GAMBLE COMPANY (US) 1999-02-18 WO disclosed
JP-H0881351-A CUTICLE KERATINIZATION PROMOTING AGENT KANEBO LTD 1996-03-26 JP disclosed
JP-S62215510-A EMULSIFIED COMPOSITION SHISEIDO CO LTD 1987-09-22 JP disclosed