SCHEMBL3228079

SCHEMBL3228079

CC(C)CC1NC(=O)COC1=O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.36
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SOAT2 O75908 1/20 0.34
SOAT1 P35610 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.31
PAX8 Q06710 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29986141 1.00 GAA (0.36) GAALMNACYP3A4CYP2C9CYP2C19
SCHEMBL3228085 1.00 GAA (0.36) GAALMNACYP3A4CYP2C9CYP2C19
SCHEMBL31692716 1.00 GAA (0.36) GAALMNACYP3A4CYP2C9CYP2C19
SCHEMBL12555541 0.93 SOAT2 (0.38) GAALMNACYP3A4CYP2C9CYP2C19
SCHEMBL15178888 0.73 MAPT (0.31) MAPT
SCHEMBL12588536 0.73 MAPT (0.31) MAPT
SCHEMBL9868912 0.71 GAA (0.38) GAALMNACYP3A4CYP2C9CYP2C19
SCHEMBL5924360 0.71 GAA (0.38) GAALMNACYP3A4CYP2C9CYP2C19
SCHEMBL439631 0.71 CACNA1G (0.32)
SCHEMBL5924203 0.71 PIK3CD (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109078221-B Small-caliber artificial blood vessel co-modified by polyethylene glycol and polypeptide and preparation method thereof 天津大学 2021-05-14 CN claimed
EP-3625292-B1 METHOD OF PREPARING A PHYSICALLY CROSS-LINKED, LACTIDE-BASED POLYMER SYSTEM, POLYMER SYSTEM PREPARED BY THE METHOD, AND PROCESS OF MANUFACTURING AN OBJECT FROM THE POLYMER SYSTEM HELMHOLTZ ZENTRUM HEREON GMBH (DE) 2022-07-06 EP disclosed
CN-109078221-B Small-caliber artificial blood vessel co-modified by polyethylene glycol and polypeptide and preparation method thereof 天津大学 2021-05-14 CN disclosed
US-20200216606-A1 Method of preparing a physically cross-linked, lactide-based polymer system, polymer system prepared by the method, and process of manufacturing an object from the polymer system. HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUER MATERIAL- UND KUESTENFORSCHUNG GMBH (DE) 2020-07-09 US disclosed
EP-3625292-A1 METHOD OF PREPARING A PHYSICALLY CROSS-LINKED, LACTIDE-BASED POLYMER SYSTEM, POLYMER SYSTEM PREPARED BY THE METHOD, AND PROCESS OF MANUFACTURING AN OBJECT FROM THE POLYMER SYSTEM Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2020-03-25 EP disclosed
WO-2019063609-A1 METHOD OF PREPARING A PHYSICALLY CROSS-LINKED, LACTIDE-BASED POLYMER SYSTEM, POLYMER SYSTEM PREPARED BY THE METHOD, AND PROCESS OF MANUFACTURING AN OBJECT FROM THE POLYMER SYSTEM Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2019-04-04 WO disclosed
US-20100062036-A1 Multiblock Copolymers with Shape-Memory Properties GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) 2010-03-11 US disclosed
US-5466801-A Process for the preparation of 3-, 6-substituted 2,5-morpholinediones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-11-14 US disclosed
EP-0322154-B1 Bioabsorbable polydepsipeptides, their preparation and use PFIZER (US) 1995-06-28 EP disclosed
WO-1994003441-A1 PROCESS FOR THE PREPARATION OF 3-, 6-SUBSTITUTED 2,5-MORPHOLINEDIONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-17 WO disclosed
US-4994551-A Sutures PFIZER INC. (US) 1991-02-19 US disclosed
US-4916209-A SURGICAL SUTURES AND CLIPS PFIZER INC. (US) 1990-04-10 US disclosed
EP-0322154-A2 Bioabsorbable polydepsipeptides, their preparation and use PFIZER INC. (US) 1989-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062036-A1 Multiblock Copolymers with Shape-Memory Properties PUF60, DDOST, PCBP1 GAA 513/4885LMNA 2720/4885CYP3A4 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.