Triaziquone

Triaziquone

SCHEMBL322828

CC(N)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.42
HTT P42858 3/20 0.40
MAPT P10636 3/20 0.40
TP53 P04637 1/20 0.40
STAT3 P40763 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP2 O95551 3/20 0.36
NSD2 O96028 3/20 0.36
APAF1 O14727 2/20 0.36
HKDC1 Q2TB90 2/20 0.36
KMT2A Q03164 2/20 0.34
ATG4B Q9Y4P1 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GALK1 P51570 1/20 0.34
BLM P54132 1/20 0.34
ATM Q13315 1/20 0.34
NOD2 Q9HC29 1/20 0.34
ADRA1D P25100 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL3100107 0.93 DNMT1 (0.44) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL7720256 0.93 DNMT1 (0.44) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL11545270 0.90 DNMT1 (0.42) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL5803947 0.90 DNMT1 (0.42) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL10583104 0.89 DNMT1 (0.47) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL322031 0.89 DNMT1 (0.39) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL5306870 0.89 DNMT1 (0.39) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL10906735 0.87 HTT (0.43) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL8333670 0.87 DNMT1 (0.38) DNMT1HTTMAPTTP53STAT3
Triaziquone SCHEMBL2941551 0.87 DNMT1 (0.38) DNMT1HTTMAPTTP53STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3918040-A1 USE OF A PARAFFINIC HYDROCARBON-BASED FUEL COMPOSITION FOR CLEANING THE INTERNAL PARTS OF DIESEL ENGINES TotalEnergies Marketing Services (FR) 2021-12-08 EP disclosed
WO-2020156941-A1 USE OF A PARAFFINIC HYDROCARBON-BASED FUEL COMPOSITION FOR CLEANING THE INTERNAL PARTS OF DIESEL ENGINES TOTAL MARKETING SERVICES (FR) 2020-08-06 WO disclosed
US-9387190-B2 Sustained release of topical anesthetics UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2016-07-12 US disclosed
US-20150297550-A1 SUSTAINED RELEASE OF TOPICAL ANESTHETICS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2015-10-22 US disclosed
EP-2914258-A1 SUSTAINED RELEASE OF TOPICAL ANESTHETICS University Of Kentucky Research Foundation (US) 2015-09-09 EP disclosed
WO-2014071203-A1 SUSTAINED RELEASE OF TOPICAL ANESTHETICS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2014-05-08 WO disclosed
EP-2590757-A1 METHOD FOR PRODUCING FINELY STRUCTURED SURFACES Leibniz-Institut für Neue Materialien gemeinnützige GmbH (DE) 2013-05-15 EP disclosed
WO-2012004319-A1 METHOD FOR PRODUCING FINELY STRUCTURED SURFACES LEIBNIZ-INSTITUT FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) 2012-01-12 WO disclosed
US-4452800-A ANTIALLERGENS, ANTIHISTAMINES, ANTIANAPHYLACTIC AGENTS SCHERING CORPORATION (US) 1984-06-05 US disclosed