Triaziquone

Triaziquone

SCHEMBL3100107

CC(C)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.44
MAPT P10636 4/20 0.42
HTT P42858 3/20 0.42
TP53 P04637 1/20 0.42
STAT3 P40763 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NSD2 O96028 4/20 0.38
TDP2 O95551 3/20 0.38
APAF1 O14727 2/20 0.38
HKDC1 Q2TB90 2/20 0.38
KMT2A Q03164 2/20 0.36
ATG4B Q9Y4P1 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GALK1 P51570 1/20 0.36
BLM P54132 1/20 0.36
ATM Q13315 1/20 0.36
NOD2 Q9HC29 1/20 0.36
TTR P02766 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL11545270 0.93 DNMT1 (0.42) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL322828 0.93 DNMT1 (0.42) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL5803947 0.93 DNMT1 (0.42) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL10583104 0.92 DNMT1 (0.47) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL7783197 0.90 MAPT (0.46) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL6245984 0.90 DNMT1 (0.40) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL6535620 0.90 DNMT1 (0.40) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL7720256 0.89 DNMT1 (0.44) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL2063810 0.89 MAPT (0.44) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL5306870 0.89 DNMT1 (0.39) DNMT1MAPTHTTTP53STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1554680-A In mold addition polymerization composition of norbornene-type monomers and its crosslinking addition polymer ס�ѵ�ľ��ʽ���� 2004-12-15 CN claimed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN claimed
CN-116103633-A Selective deposition of materials comprising silicon and oxygen using plasma ASM IP私人控股有限公司 2023-05-12 CN disclosed
CN-116065133-A Selective deposition using thermal and plasma enhanced methods ASM IP私人控股有限公司 2023-05-05 CN disclosed
CN-116065134-A Selective thermal deposition method ASM IP私人控股有限公司 2023-05-05 CN disclosed
US-20100255098-A1 STEREOCOMPLEX HYDROGELS UNIVERSITEIT UTRECHT (NL) 2010-10-07 US disclosed
US-20070185008-A1 Stereocomplex hydrogels with tunable degradation times CHIENNA B.V. (NL) 2007-08-09 US disclosed
WO-2006121058-A1 ORGANOMETALLIC COMPOUND, CATALYST FOR POLYMERIZATION OF POLAR GROUP-CONTAINING NORBORNENE AND PROCESS FOR PRODUCING NORBORNENE POLYMER FUJIFILM CORPORATION (JP) 2006-11-16 WO disclosed
EP-1699837-A1 STEREOCOMPLEX HYDROGELS WITH TUNABLE DEGRADATION TIMES Universiteit Utrecht (NL) 2006-09-13 EP disclosed
WO-2005054318-A1 STEREOCOMPLEX HYDROGELS WITH TUNABLE DEGRADATION TIMES UNIVERSITEIT UTRECHT (NL) 2005-06-16 WO disclosed
CN-1555387-A Polymer composition for manufacturing optical waveguide, optical waveguide manufactured thereby, and method for manufacturing the waveguide 古德里奇公司 2004-12-15 CN disclosed
EP-1183016-A1 STEREOCOMPLEX HYDROGELS Universiteit Utrecht (NL) 2002-03-06 EP disclosed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN disclosed
WO-2000048576-A1 STEREOCOMPLEX HYDROGELS UNIVERSITEIT UTRECHT (NL) 2000-08-24 WO disclosed