Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 10/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238138 | 1.00 | ADK (0.40) | ADKPRMT5WDR77DNMT1DNMT3B | |
| SCHEMBL3238152 | 0.85 | PRMT5 (0.41) | ADKPRMT5WDR77DNMT1DNMT3B | |
| Salicylic Acid SCHEMBL3238127 | 0.84 | PRMT5 (0.42) | ADKPRMT5WDR77DNMT1DNMT3B | |
| SCHEMBL3229893 | 0.77 | PRMT5 (0.50) | ADKPRMT5WDR77ADORA2A | |
| SCHEMBL21006387 | 0.77 | PRMT5 (0.50) | ADKPRMT5WDR77ADORA2A | |
| SCHEMBL19537076 | 0.77 | PRMT5 (0.50) | ADKPRMT5WDR77ADORA2A | |
| SCHEMBL17109566 | 0.77 | PRMT5 (0.50) | ADKPRMT5WDR77ADORA2A | |
| SCHEMBL3234238 | 0.77 | PRMT5 (0.50) | ADKPRMT5WDR77ADORA2A | |
| SCHEMBL19535607 | 0.77 | PRMT5 (0.50) | ADKPRMT5WDR77ADORA2A | |
| SCHEMBL1736124 | 0.77 | PRMT5 (0.50) | ADKPRMT5WDR77ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015643-A1 | NEW ANTIVIRAL MODIFIED NUCLEOSIDES | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | disclosed |