SCHEMBL1736124

SCHEMBL1736124

C#C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc2c(N)ncnc21

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 15/20 0.50
▸ WDR77 Q9BQA1 11/20 0.50
▸ ADK P55263 2/20 0.50
▸ ADORA2A P29274 1/20 0.47
▸ METTL3 Q86U44 1/20 0.43
▸ DOT1L Q8TEK3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19537076 1.00 PRMT5 (0.50) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL16373988 1.00 PRMT5 (0.50) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL21006387 1.00 PRMT5 (0.50) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL19535607 1.00 PRMT5 (0.50) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL17109566 1.00 PRMT5 (0.50) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL3234238 1.00 PRMT5 (0.50) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL3229893 1.00 PRMT5 (0.50) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL21008034 0.91 PRMT5 (0.47) PRMT5WDR77ADKADORA2AMETTL3
Salicylic Acid SCHEMBL3238127 0.88 PRMT5 (0.42) PRMT5WDR77ADKADORA2A
SCHEMBL19379664 0.88 ADORA2A (0.48) PRMT5WDR77ADKADORA2AMETTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-04-16 — — US claimed
EP-4491232-A2 N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO Emory University (US) 2025-01-15 — — EP claimed
EP-3706762-B1 N4-HYDROXYCYTIDINE DERIVATIVE AND ANTI-VIRAL USES RELATED THERETO UNIV EMORY (US) 2024-10-16 — — EP claimed
WO-2024192348-A2 METHODS OF TREATING HPV IN HIV-INFECTED PATIENTS OHIO STATE INNOVATION FOUNDATION (US) 2024-09-19 — — WO claimed
US-12083185-B2 Small polymeric carriers for delivery of agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-09-10 — — US claimed
US-20240165143-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY 2024-05-23 — — US claimed
CN-114867351-B 4' -Halogen-containing nucleotide and nucleoside therapeutic compositions and related uses 埃默里大学 2024-04-23 — — CN claimed
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO., INC. (US) 2023-05-11 — — US claimed
EP-4149552-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG Healion Bio, Inc. (US) 2023-03-22 — — EP claimed
CN-115666587-A N4-hydroxycytidine and derivatives and related antiviral uses thereof 埃默里大学 2023-01-31 — — CN claimed
EP-4017501-A1 N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO Emory University (US) 2022-06-29 — — EP claimed
EP-3963087-A1 IDENTIFICATION AND ANALYSIS OF MICROBIAL SAMPLES BY RAPID INCUBATION AND NUCLEIC ACID ENRICHMENT Illumina Inc (US) 2022-03-09 — — EP claimed
US-8278282-B2 Nucleoside analogs for treatment of viral infections NOVARTIS AG (CH) 2012-10-02 — — US claimed
EP-2132216-B1 NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS NOVARTIS PHARMA AG (CH) 2011-11-16 — — EP claimed
WO-2011131167-A2 BISTABLE MAGNETIC ACTUATOR JOHNSON ELECTRIC DRESDEN GMBH (DE) 2011-10-27 — — WO claimed
US-20100227833-A1 NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS NOVARTIS PHARMA AG (CH) 2010-09-09 — — US claimed
US-20100144655-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-06-10 — — US claimed
WO-2010015643-A1 NEW ANTIVIRAL MODIFIED NUCLEOSIDES NOVARTIS AG (CH) 2010-02-11 — — WO claimed
EP-2132216-A1 NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS Novartis Pharma AG. (CH) 2009-12-16 — — EP claimed
WO-2008095993-A1 NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS NOVARTIS AG (CH) 2008-08-14 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO SARS1, ITK, SLC43A1 PRMT5 3184/4885WDR77 4066/4885ADK 470/4885
US-20100227833-A1 NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS MAVS, HAVCR2, SAMHD1 PRMT5 1421/4885WDR77 842/4885ADK 283/4885
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES CTSV, CTSB, CTSS PRMT5 2463/4885WDR77 1820/4885ADK 1637/4885
US-12083185-B2 Small polymeric carriers for delivery of agents CD44, PGF, SLC46A1 PRMT5 4434/4885WDR77 3228/4885ADK 4798/4885
US-20100144655-A1 ORGANIC COMPOUNDS OAT, MAVS, HAVCR2 PRMT5 1914/4885WDR77 3894/4885ADK 3634/4885
US-20240165143-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, PRPF4, HPRT1 PRMT5 2436/4885WDR77 2039/4885ADK 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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