SCHEMBL2272164

SCHEMBL2272164

COc1ccc(CSc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.69
MAOB P27338 3/20 0.63
MAOA P21397 2/20 0.63
LTA4H P09960 2/20 0.57
MCL1 Q07820 1/20 0.56
ALDH1A1 P00352 3/20 0.52
LMNA P02545 2/20 0.52
HDAC3 O15379 1/20 0.52
NCOR1 O75376 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
MEN1 O00255 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
KMT2A Q03164 1/20 0.51
RELA Q04206 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2433694 0.92 APP (0.69) APPMAOBMAOALTA4HMCL1
Isothiocyanate SCHEMBL6154852 0.92 APP (0.59) APPMAOBMAOALTA4HMCL1
SCHEMBL3228582 0.90 APP (0.82) APPMAOBMAOAALDH1A1HDAC3
SCHEMBL19059386 0.85 APP (0.74) APPMAOBMAOAALDH1A1LMNA
SCHEMBL11044221 0.85 APP (0.74) APPMAOBMAOAALDH1A1LMNA
SCHEMBL10055053 0.83 ALDH1A1 (0.57) MAOBMAOALTA4HALDH1A1LMNA
SCHEMBL28526426 0.83 APP (0.72) APPMAOBMAOAALDH1A1HDAC3
SCHEMBL19869138 0.81 LTA4H (0.53) APPMAOBMAOALTA4HMCL1
SCHEMBL12945246 0.81 APP (0.70) APPMAOBMAOAALDH1A1LMNA
SCHEMBL9475495 0.81 APP (0.70) APPMAOBMAOALTA4HMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181122-A Benzyl thioether compound and preparation method thereof 苏州照固新材料科技有限公司 2022-03-15 CN disclosed
CN-104254525-A Aromatic ring compound TAKEDA PHARMACEUTICAL 2014-12-31 CN disclosed
EP-2071373-B1 METHOD FOR PRODUCING SELF-FORMATION OPTICAL WAVEGUIDE TOYOTA CHUO KENKYUSHO KK (JP) 2014-11-05 EP disclosed
US-8170385-B2 Light coupler and manufacturing method thereof TOYODA GOSEI CO., LTD. (JP) 2012-05-01 US disclosed
US-7998374-B2 Fabrication method of self-written optical waveguide KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2011-08-16 US disclosed
US-7899287-B2 Optical branching-coupling device, and manufacturing method and optical module of the same TOYODA GOSEI CO., LTD. (JP) 2011-03-01 US disclosed
US-20100137608-A1 POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-06-03 US disclosed
US-7683218-B2 Method for producing thioether compound BANYU PHARMACEUTICAL CO., LTD. (JP) 2010-03-23 US disclosed
US-7683218-B2 Method for producing thioether compound BANYU PHARMACEUTICAL CO., LTD. (JP) 2010-03-23 US disclosed
US-7683218-B2 Method for producing thioether compound BANYU PHARMACEUTICAL CO., LTD. (JP) 2010-03-23 US disclosed
US-7399498-B2 Material composition for producing optical waveguide and method for producing optical waveguide TOYODA GOSEI CO., LTD. (JP) 2008-07-15 US disclosed
US-20080108823-A1 Method For Producing Thioether Compound MSD K.K. (JP) 2008-05-08 US disclosed
US-20080108823-A1 Method For Producing Thioether Compound MSD K.K. (JP) 2008-05-08 US disclosed
US-20080108823-A1 Method For Producing Thioether Compound MSD K.K. (JP) 2008-05-08 US disclosed
EP-1806337-A1 METHOD FOR PRODUCING THIOETHER COMPOUND BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-07-11 EP disclosed
EP-1806337-A1 METHOD FOR PRODUCING THIOETHER COMPOUND BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-07-11 EP disclosed
EP-1416301-A9 Material composition for producing optical waveguide and method for producing optical waveguide Toyoda Gosei Co., Ltd. (JP) 2004-07-14 EP disclosed
US-20040131320-A1 Material composition for producing optical waveguide and method for producing optical waveguide TOYODA GOSEI CO., LTD. (JP) 2004-07-08 US disclosed
EP-1416301-A1 Material composition for producing optical-waveguide and method for producing optical waveguide Toyoda Gosei Co., Ltd. (JP) 2004-05-06 EP disclosed
US-4478984-A CONDENSING AN N-(CHLOROBENZYL)-PHTHALIMIDE WITH A STYRENE RESIN AND SPLITTING THE IMIDE SMITHKLINE BECKMAN CORPORATION (US) 1984-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137608-A1 POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS SCO2, CYCS, NCLN APP 4557/4885MAOB 1507/4885MAOA 2009/4885
US-20080108823-A1 Method For Producing Thioether Compound TST, MPST, PPIP5K2 APP 3047/4885MAOB 2009/4885MAOA 3064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.