Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31671096 | 1.00 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTTSHRTDP1 | |
| SCHEMBL3218848 | 0.85 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTTSHRTDP1 | |
| SCHEMBL31671095 | 0.85 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTTSHRTDP1 | |
| SCHEMBL28221126 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAMAPTTSHRTDP1 | |
| SCHEMBL31671088 | 0.82 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTTSHRTDP1 | |
| SCHEMBL3223745 | 0.82 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTTSHRTDP1 | |
| SCHEMBL19554031 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTTDP1KMT2A | |
| SCHEMBL4737147 | 0.81 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTKMT2APLK1 | |
| SCHEMBL2573788 | 0.81 | ABL1 (0.65) | ALDH1A1GAAMAPTKMT2APLK1 | |
| SCHEMBL3222277 | 0.80 | ABL1 (0.52) | ALDH1A1GAAPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12629371-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-11725005-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-20230159514-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-11407747-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-20210130343-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2021-05-06 | — | — | US | disclosed |
| US-10906896-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200046699-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2020-02-13 | — | — | US | disclosed |
| US-20200031819-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2020-01-30 | — | — | US | disclosed |
| EP-3532066-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | Inhibikase Therapeutics, Inc. (US) | 2019-09-04 | — | — | EP | disclosed |
| US-10344027-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-9828370-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-9828370-B2 | Compositions and methods for inhibiting kinases | INHIBIKASE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| WO-2016172528-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160311816-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2016-10-27 | — | — | US | disclosed |
| US-20160311816-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2016-10-27 | — | — | US | disclosed |
| US-20100048539-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048539-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048539-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| EP-2079729-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008058037-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048539-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | PDGFRB, PDGFRA, KIT | ALDH1A1 2082/4885GAA 1005/4885MAPT 3837/4885 |
| US-10344027-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-20200031819-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-20160311816-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-12629371-B2 | Compositions and methods for inhibiting kinases | PTK2, HCK, PTK2B | ALDH1A1 1607/4885GAA 1226/4885MAPT 1672/4885 |
| US-10906896-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-11407747-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-20210130343-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-20230159514-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-11725005-B2 | Compositions and methods for inhibiting kinases | MAP3K1, PACSIN2, MAP3K3 | ALDH1A1 4642/4885GAA 2261/4885MAPT 2703/4885 |
| US-20200046699-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | ABL1, FYN, PTK2 | ALDH1A1 4081/4885GAA 670/4885MAPT 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.