SCHEMBL3229694

SCHEMBL3229694

CCCCCNOc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.47
SIGMAR1 Q99720 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.45
NAAA Q02083 1/20 0.43
HTR1B P28222 1/20 0.41
EPHX1 P07099 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HTT P42858 2/20 0.41
KCNH3 Q9ULD8 1/20 0.41
MLNR O43193 1/20 0.41
NR1I2 O75469 1/20 0.41
ESR1 P03372 1/20 0.41
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
ADRB2 P07550 1/20 0.41
CHRM2 P08172 1/20 0.41
ADRB1 P08588 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3222529 0.98 ZDHHC2 (0.48) LTA4HSIGMAR1ZDHHC2NAAAEPHX1
SCHEMBL3213441 0.98 ZDHHC2 (0.48) LTA4HSIGMAR1ZDHHC2NAAAEPHX1
SCHEMBL3229711 0.98 ZDHHC2 (0.48) LTA4HSIGMAR1ZDHHC2NAAAEPHX1
SCHEMBL3227303 0.94 LTA4H (0.47) LTA4HSIGMAR1ZDHHC2HTR1BALDH1A1
Sulfuric Acid SCHEMBL27511040 0.90 ZDHHC2 (0.49) ZDHHC2NAAAEPHX1ALDH1A1HTT
SCHEMBL6114670 0.88 SOAT2 (0.47) ZDHHC2CNR1
Acetic Acid SCHEMBL7350357 0.85 HDAC3 (0.49) ZDHHC2NAAAALDH1A1HTTLMNA
SCHEMBL1033246 0.85 HTR1B (0.42) LTA4HSIGMAR1ZDHHC2HTR1BDRD2
Fluoride SCHEMBL27524402 0.83 HTR1B (0.41) LTA4HSIGMAR1ZDHHC2HTR1BALDH1A1
SCHEMBL14307856 0.83 HDAC3 (0.46) LTA4HALDH1A1HTTLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010004016-A1 USE OF PHENOXYALKYLAMINES IN COSMETIC AND/OR DERMATOLOGICAL COMPOSITIONS L'OREAL (FR) 2010-01-14 WO disclosed
US-4430420-A USING AN AMINOSULFONYLHYDRAZONE REDUCING AGENT EASTMAN KODAK COMPANY (US) 1984-02-07 US disclosed
US-4053611-A SUBSTITUTED PHENOXYALKYL QUATERNARY AMMONIUM COMPOUNDS AS ANTIARRHYTHEMIC AGENTS THE DOW CHEMICAL COMPANY (US) 1977-10-11 US disclosed