Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591586 | 0.98 | CSNK1E (0.47) | CSNK1ELTA4HSLC2A1CNR2SLC7A5 | |
| SCHEMBL3222538 | 0.98 | CSNK1E (0.47) | CSNK1ELTA4HSLC2A1CNR2SLC7A5 | |
| SCHEMBL3213449 | 0.98 | CSNK1E (0.47) | CSNK1ELTA4HSLC2A1CNR2SLC7A5 | |
| SCHEMBL3229708 | 0.94 | LTA4H (0.44) | CSNK1ELTA4HCNR2SLC7A5SLC6A4 | |
| SCHEMBL3227309 | 0.86 | SLC6A4 (0.41) | LTA4HSLC7A5SLC6A4MAOALMNA | |
| SCHEMBL27624167 | 0.85 | CSNK1E (0.43) | CSNK1ELTA4HSLC2A1CNR2SLC6A4 | |
| SCHEMBL3483450 | 0.85 | SLC2A1 (0.40) | CSNK1ELTA4HSLC2A1CNR2SLC7A5 | |
| SCHEMBL3483448 | 0.85 | SLC2A1 (0.40) | CSNK1ELTA4HSLC2A1CNR2SLC7A5 | |
| SCHEMBL15500085 | 0.82 | SLC2A1 (0.46) | CSNK1ESLC2A1OPRM1HTT | |
| SCHEMBL4445054 | 0.81 | LTA4H (0.47) | CSNK1ELTA4HCNR2SLC7A5SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501939-B2 | Compounds derived from triazine chemistry are known to be useful for the affinity purification of proteins; compounds derivatised with linear, branched or cyclic alkyl groups and devoid of any additional hydrophilic or charged or groups, are especially useful for the purification of proteins with hydroph | PROMETIC BIOSCIENCES LIMITED (GB) | 2013-08-06 | — | — | US | disclosed |
| US-8450348-B2 | Such as 3-[6-(4-Chloro-phenoxy)-hexylamino]-4-(pyridin-4-ylamino)-cyclobut-3-ene-1,2-dione; cancer, tumors; reduced side effects | FORMA TM, LLC (US) | 2013-05-28 | — | — | US | disclosed |
| WO-2010004016-A1 | USE OF PHENOXYALKYLAMINES IN COSMETIC AND/OR DERMATOLOGICAL COMPOSITIONS | L'OREAL (FR) | 2010-01-14 | — | — | WO | disclosed |
| US-20080207876-A1 | Triazines and Pyrimidines as Protein Binding Ligands | PROMETIC BIOSCIENCES LIMITED (GB) | 2008-08-28 | — | — | US | disclosed |
| US-20080200523-A1 | Derivatives of squaric acid with anti-proliferative activity | Valo Health, LLC | 2008-08-21 | — | — | US | disclosed |
| CN-101203497-A | Triazines as protein binding ligands | PROMETIC BIOSCIENCES LTD (GB) | 2008-06-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207876-A1 | Triazines and Pyrimidines as Protein Binding Ligands | NR4A2, NR5A2, NR2C2 | CSNK1E 1874/4885LTA4H 3596/4885SLC2A1 2423/4885 |
| US-20080200523-A1 | Derivatives of squaric acid with anti-proliferative activity | SQLE, FDFT1, DLD | CSNK1E 2830/4885LTA4H 3588/4885SLC2A1 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.