Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320656 | 0.88 | HPGD (0.54) | HPGDDAGLAADORA2AADORA1ABCG2 | |
| SCHEMBL4409336 | 0.86 | HPGD (0.49) | HPGDABCG2 | |
| SCHEMBL4414660 | 0.84 | HPGD (0.50) | HPGDDAGLAABCG2 | |
| SCHEMBL4412019 | 0.82 | HPGD (0.51) | HPGDDAGLAABCG2MAOA | |
| SCHEMBL3226588 | 0.80 | DAGLA (0.42) | DAGLAFAAHCES1 | |
| SCHEMBL4409289 | 0.80 | HPGD (0.55) | HPGDDAGLAADORA2AADORA2BADORA1 | |
| SCHEMBL4409279 | 0.78 | HPGD (0.54) | HPGDDAGLAABCG2 | |
| SCHEMBL2162217 | 0.77 | FAAH (0.41) | HPGDFAAHCES1TP53 | |
| SCHEMBL2162009 | 0.76 | CES1 (0.72) | DAGLAADORA2AFAAHCES1 | |
| SCHEMBL512253 | 0.75 | HPGD (0.63) | HPGDABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005572-A2 | ALPHA-KETO HETEROCYCLES AS FAAH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-01-14 | — | — | WO | disclosed |