Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414660 | 0.95 | HPGD (0.50) | HPGDABCG2ABCB1DAGLAHSD11B1 | |
| SCHEMBL4409336 | 0.94 | HPGD (0.49) | HPGDABCG2ABCB1HSD11B1GPR84 | |
| SCHEMBL4409279 | 0.90 | HPGD (0.54) | HPGDABCG2ABCB1DAGLANPC1 | |
| SCHEMBL4407303 | 0.82 | HPGD (0.57) | HPGDABCG2ABCB1NPC1RAB9A | |
| SCHEMBL3229757 | 0.82 | HPGD (0.50) | HPGDABCG2DAGLAMAOA | |
| SCHEMBL512253 | 0.77 | HPGD (0.63) | HPGDABCG2ABCB1NPC1RAB9A | |
| SCHEMBL513770 | 0.75 | HPGD (0.57) | HPGDABCG2ABCB1NPC1RAB9A | |
| SCHEMBL4405944 | 0.75 | HPGD (0.53) | HPGDABCG2CNR1CNR2NPC1 | |
| SCHEMBL4412042 | 0.75 | HPGD (0.53) | HPGDABCG2ABCB1NPC1RAB9A | |
| SCHEMBL4404217 | 0.74 | RAB9A (0.53) | DAGLAHSD11B1NPC1RAB9ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |