Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.69 |
| ▸ | NPC1 | O15118 | 11/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600999 | 0.95 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL1837292 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL7995030 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL6767997 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL8076542 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL7653371 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL1834100 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL8600460 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL10599124 | 0.93 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2RECQLHPGD | |
| SCHEMBL7564852 | 0.91 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2RECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356173-A | Novel pyridopyrazines and their use as modulators of kinases | AETERNA ZENTARIS GMBH (DE) | 2009-01-28 | — | — | CN | claimed |
| US-7405319-B2 | Process for the preparation of carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-07-29 | — | — | US | claimed |
| US-20070270605-A1 | Process for the preparation of carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-11-22 | — | — | US | claimed |
| CN-1382119-A | Substituted alpha-hydroxy acid caspase inhibitors and uses thereof | CYTOVIA INC (US) | 2002-11-27 | — | — | CN | claimed |
| US-5091556-A | Catalytic reacting carbonate with amine | ENICHEM SYNTHESIS, S.P.A. (IT) | 1992-02-25 | — | — | US | claimed |
| US-5079383-A | With A Methylating Agent Using A Zinc Halide Catalyst | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-07 | — | — | US | claimed |
| US-12623999-B2 | Carbamate production method, carbamate ester production method, and urea derivative production method | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2026-05-12 | — | — | US | disclosed |
| EP-4612156-A1 | ANTI-VIRAL COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| US-20240425448-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-12-26 | — | — | US | disclosed |
| EP-4431490-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118215651-A | Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition | 旭化成株式会社 | 2024-06-18 | — | — | CN | disclosed |
| WO-2024097296-A1 | ANTI-VIRAL COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| US-20230212110-A1 | CARBAMATE PRODUCTION METHOD, CARBAMATE ESTER PRODUCTION METHOD, AND UREA DERIVATIVE PRODUCTION METHOD | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2023-07-06 | — | — | US | disclosed |
| US-4260781-A | Process for the manufacture of carbamates | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4258201-A | CATALYTIC CARBONYLATION OF PRIMARY OR SECONDARY AMINES WITH CARBON MONOXIDE AND ALCOHOLS | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4243815-A | Preparation of methylene-bis(4-phenylcarbamic acid esters) | BASF AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4242520-A | ONE-STEP CARBONYLATION OF AMINES IN THE PRESENCE OF A DISULFIDE | HALCON RESEARCH & DEVELOPMENT CORPORATION (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0014103-A2 | Improved process for the manufacture of carbamates | THE HALCON SD GROUP, INC. (US) | 1980-08-06 | — | — | EP | disclosed |
| US-4081472-A | CATALYTIC, FROM A CARBAMATE | MITSUI TOATSU CHEMICALS INC. (JA) | 1978-03-28 | — | — | US | disclosed |
| US-3938986-A | ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE | PPG INDUSTRIES, INC. (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12623999-B2 | Carbamate production method, carbamate ester production method, and urea derivative production method | CPS1, CA2, CHRM2 | RAB9A 1485/4885NPC1 835/4885SMN1; SMN2 3022/4885 |
| US-20230212110-A1 | CARBAMATE PRODUCTION METHOD, CARBAMATE ESTER PRODUCTION METHOD, AND UREA DERIVATIVE PRODUCTION METHOD | CPS1, ATM, OAT | RAB9A 2285/4885NPC1 617/4885SMN1; SMN2 4152/4885 |
| US-20240425448-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION | IDH3A, CA7, C9 | RAB9A 3205/4885NPC1 666/4885SMN1; SMN2 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.