Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | CTSV | O60911 | 3/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689438 | 0.83 | HPGD (0.35) | MAPTMCL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL688804 | 0.81 | CMA1 (0.38) | MCL1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL689572 | 0.81 | PTGDR2 (0.38) | MCL1MEN1ALDH1A1KMT2ACA1 | |
| SCHEMBL3229944 | 0.76 | MCL1 (0.57) | MAOAGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL4198025 | 0.76 | MCL1 (0.57) | MAPTDAOMCL1KDM4EMEN1 | |
| SCHEMBL692868 | 0.73 | LMNA (0.42) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7879482 | 0.72 | L3MBTL1 (0.50) | MAPTCTSVMCL1KDM4EALDH1A1 | |
| SCHEMBL3269248 | 0.71 | JAK2 (0.41) | MAOAMAOB | |
| SCHEMBL16644709 | 0.71 | KDM4E (0.42) | MAPTMAOACTSVDAOMCL1 | |
| SCHEMBL11467251 | 0.69 | DAO (0.45) | MAPTMAOACTSVDAOMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |