Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291321 | 0.71 | STAT3 (0.30) | — | |
| SCHEMBL2933399 | 0.69 | KCNH2 (0.40) | — | |
| SCHEMBL2767122 | 0.64 | KCNH2 (0.36) | — | |
| SCHEMBL30609565 | 0.64 | KMT2A (0.49) | LMNAALDH1A1HTTSMN1; SMN2CYP2D6 | |
| SCHEMBL15286533 | 0.64 | KMT2A (0.45) | LMNAALDH1A1HTTSMN1; SMN2CYP2D6 | |
| SCHEMBL26906068 | 0.63 | STAT3 (0.39) | LMNAALDH1A1HTTSMN1; SMN2CYP2D6 | |
| SCHEMBL21768407 | 0.63 | KMT2A (0.43) | ALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL18047923 | 0.63 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL4934980 | 0.62 | STAT3 (0.43) | LMNAALDH1A1HTTSMN1; SMN2CYP2D6 | |
| SCHEMBL17543713 | 0.62 | ALDH1A1 (0.38) | LMNAALDH1A1HTTSMN1; SMN2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | LMNA 2142/4885ALDH1A1 4233/4885HTT 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.