SCHEMBL3230289

SCHEMBL3230289

CCN(C(C)=O)C(CS)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
NFKB1 P19838 1/20 0.36
PTGS2 P35354 1/20 0.36
THPO P40225 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PTGS1 P23219 1/20 0.33
SLC7A11 Q9UPY5 1/20 0.33
ENPEP Q07075 3/20 0.31
KDR P35968 1/20 0.31
CPN1 P15169 1/20 0.31
CPB2 Q96IY4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38660143 1.00 KDM4E (0.36) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL7646334 1.00 KDM4E (0.36) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL515406 0.85 PTGS1 (0.34) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL7360975 0.85 PTGS1 (0.34) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL2028307 0.85 PTGS1 (0.34) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL31682890 0.84 KDM4E (0.34) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL27832923 0.82 PTGS1 (0.37) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4633159 0.79 ACE (0.51) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4633548 0.79 ACE (0.51) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4911434 0.79 CPB2 (0.36) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557865-B Thioether-promoted cysteine-based bioconjugate method 南京工业大学 2024-05-14 CN claimed
CN-115557865-A Thioether-promoted cysteine-based bioconjugation method 南京工业大学 2023-01-03 CN claimed
US-12157869-B2 Methods and compositions for reducing persistent odor in clothing and mitigating biofilms on various materials LINDSAY JEFFREY DEAN (US) 2024-12-03 US disclosed
CN-118924717-A Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2024-11-12 CN disclosed
CN-111683684-B Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2024-07-02 CN disclosed
CN-113473993-B Methods and compositions for treating motor neuron diseases 巴伦西亚大学 2024-06-04 CN disclosed
CN-117599029-A Compositions for controlled release of cysteamine and systematic treatment of cysteamine-sensitive disorders 硫创治疗公司 2024-02-27 CN disclosed
CN-115884764-A Cysteamine precursor compounds for treating coronavirus b infection 硫创治疗公司 2023-03-31 CN disclosed
EP-4041856-A1 METHODS AND COMPOSITIONS FOR REDUCING ODOR AND BIOFILM Lindsay, Jeffrey Dean (US) 2022-08-17 EP disclosed
CN-113473993-A Methods and compositions for treating motor neuron diseases 巴伦西亚大学 2021-10-01 CN disclosed
WO-2021076526-A1 METHODS AND COMPOSITIONS FOR REDUCING ODOR AND BIOFILM LINDSAY JEFFREY DEAN (US) 2021-04-22 WO disclosed
US-20160029626-A1 CYSTEINE AMINO-ACID COMPOUND (OR ITS ANALOGUES) USED IN THE DISRUPTION OF MICROBIAL BIOFILMS WHEN TREATING OR PREVENTING DISEASES CAUSED BY PHYTOPATHOGENIC BACTERIA KNOWN TO ATTACK PLANTS OF AGRICULTURAL INTEREST INSTITUTO AGRONOMICO DE CAMPINAS - IAC (BR) 2016-02-04 US disclosed
US-20140024857-A1 CYSTEINE AMINO-ACID COMPOUND (OR ITS ANALOGUES) USED IN THE DISRUPTION OF MICROBIAL BIOFILMS WHEN TREATING OR PREVENTING DISEASES CAUSED BY PHYTOPATHOGENIC BACTERIA KNOWN TO ATTACK PLANTS OF AGRICULTURAL INTEREST INSTITUTO AGRONOMICO DE CAMPINAS - IAC (BR) 2014-01-23 US disclosed
WO-2010023505-A1 COATED PARTICLES OF N-ACETYL-3-MERCAPTOALANINE WITH SWEETENERS ABDI IBRAHIM ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) 2010-03-04 WO disclosed
US-6475434-B1 Composition and methods for preventing and removing biofilm embedded microorganisms from the surface of medical devices BAYLOR COLLEGE OF MEDICINE 2002-11-05 US disclosed
WO-2000033895-A1 PREVENTING AND REMOVING BIOFILM FROM THE SURFACE OF MEDICAL DEVICES BAYLOR COLLEGE OF MEDICINE (US) 2000-06-15 WO disclosed
US-5733535-A Topical compositions containing N-acetylcysteine and odor masking materials THE PROCTER & GAMBLE CO. (US) 1998-03-31 US disclosed
US-5691380-A SKIN DISORDERS THE PROCTER & GAMBLE COMPANY (US) 1997-11-25 US disclosed
WO-1997015283-A1 TOPICAL COMPOSITIONS CONTAINING N-ACETYLCYSTEINE AND ODOR MASKING MATERIALS THE PROCTER & GAMBLE COMPANY (US) 1997-05-01 WO disclosed
WO-1997001325-A1 STABLE N-ACETYLCYSTEINE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-01-16 WO disclosed