Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660143 | 1.00 | KDM4E (0.36) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL3230289 | 1.00 | KDM4E (0.36) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL515406 | 0.85 | PTGS1 (0.34) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL7360975 | 0.85 | PTGS1 (0.34) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2028307 | 0.85 | PTGS1 (0.34) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL31682890 | 0.84 | KDM4E (0.34) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL27832923 | 0.82 | PTGS1 (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4633159 | 0.79 | ACE (0.51) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4633548 | 0.79 | ACE (0.51) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4911434 | 0.79 | CPB2 (0.36) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241632-A | Analogues of celastrol | ERX制药股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-12157869-B2 | Methods and compositions for reducing persistent odor in clothing and mitigating biofilms on various materials | LINDSAY JEFFREY DEAN (US) | 2024-12-03 | — | — | US | disclosed |
| CN-118924717-A | Methods for treating cysteamine-sensitive disorders | 硫创治疗公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-111683684-B | Methods for treating cysteamine-sensitive disorders | 硫创治疗公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113473993-B | Methods and compositions for treating motor neuron diseases | 巴伦西亚大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-117599029-A | Compositions for controlled release of cysteamine and systematic treatment of cysteamine-sensitive disorders | 硫创治疗公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-115884764-A | Cysteamine precursor compounds for treating coronavirus b infection | 硫创治疗公司 | 2023-03-31 | — | — | CN | disclosed |
| EP-4041856-A1 | METHODS AND COMPOSITIONS FOR REDUCING ODOR AND BIOFILM | Lindsay, Jeffrey Dean (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021076526-A1 | METHODS AND COMPOSITIONS FOR REDUCING ODOR AND BIOFILM | LINDSAY JEFFREY DEAN (US) | 2021-04-22 | — | — | WO | disclosed |
| US-20210032570-A1 | METHODS AND COMPOSITIONS FOR REDUCING PERSISTENT ODOR IN CLOTHING AND MITIGATING BIOFILMS ON VARIOUS MATERIALS | Planet Lindsay, LLC (US) | 2021-02-04 | — | — | US | disclosed |
| US-20210009922-A1 | METHODS AND COMPOSITIONS FOR REDUCING PERSISTENT ODOR IN CLOTHING AND MITIGATING BIOFILMS | WELLS FARGO BANK, N.A. | 2021-01-14 | — | — | US | disclosed |
| CN-111683684-A | Methods for treating cysteamine-sensitive disorders | 硫创治疗公司 | 2020-09-18 | — | — | CN | disclosed |
| US-20160029626-A1 | CYSTEINE AMINO-ACID COMPOUND (OR ITS ANALOGUES) USED IN THE DISRUPTION OF MICROBIAL BIOFILMS WHEN TREATING OR PREVENTING DISEASES CAUSED BY PHYTOPATHOGENIC BACTERIA KNOWN TO ATTACK PLANTS OF AGRICULTURAL INTEREST | INSTITUTO AGRONOMICO DE CAMPINAS - IAC (BR) | 2016-02-04 | — | — | US | disclosed |
| US-20140024857-A1 | CYSTEINE AMINO-ACID COMPOUND (OR ITS ANALOGUES) USED IN THE DISRUPTION OF MICROBIAL BIOFILMS WHEN TREATING OR PREVENTING DISEASES CAUSED BY PHYTOPATHOGENIC BACTERIA KNOWN TO ATTACK PLANTS OF AGRICULTURAL INTEREST | INSTITUTO AGRONOMICO DE CAMPINAS - IAC (BR) | 2014-01-23 | — | — | US | disclosed |
| US-6475434-B1 | Composition and methods for preventing and removing biofilm embedded microorganisms from the surface of medical devices | BAYLOR COLLEGE OF MEDICINE | 2002-11-05 | — | — | US | disclosed |
| WO-2000033895-A1 | PREVENTING AND REMOVING BIOFILM FROM THE SURFACE OF MEDICAL DEVICES | BAYLOR COLLEGE OF MEDICINE (US) | 2000-06-15 | — | — | WO | disclosed |
| US-5733535-A | Topical compositions containing N-acetylcysteine and odor masking materials | THE PROCTER & GAMBLE CO. (US) | 1998-03-31 | — | — | US | disclosed |
| US-5691380-A | SKIN DISORDERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1997015283-A1 | TOPICAL COMPOSITIONS CONTAINING N-ACETYLCYSTEINE AND ODOR MASKING MATERIALS | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-01 | — | — | WO | disclosed |
| WO-1997001325-A1 | STABLE N-ACETYLCYSTEINE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-16 | — | — | WO | disclosed |