Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226297 | 0.77 | CDK4 (0.31) | CDK4CCND1 | |
| SCHEMBL3227968 | 0.75 | KCNH2 (0.32) | — | |
| SCHEMBL1723375 | 0.69 | HTR1A (0.43) | HTR1ADRD2 | |
| SCHEMBL1723599 | 0.69 | HTR1A (0.43) | HTR1ADRD2 | |
| SCHEMBL2292376 | 0.69 | HTR1A (0.43) | HTR1ADRD2 | |
| SCHEMBL28749697 | 0.69 | PARP1 (0.48) | — | |
| SCHEMBL4421682 | 0.66 | HTR1A (0.46) | HTR1ADRD2CDK4CCND1KDM4E | |
| SCHEMBL2291274 | 0.66 | HTR1A (0.43) | HTR1ADRD2CDK4CCND1 | |
| SCHEMBL3221898 | 0.65 | — | — | |
| SCHEMBL3149594 | 0.64 | HTR1A (0.37) | HTR1ADRD2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | HTR1A 2158/4885DRD2 890/4885CDK4 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.