Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808649 | 0.83 | PKM (1.00) | PKMGAATSHRTNFCYP11B1 | |
| SCHEMBL4958156 | 0.82 | PKM (0.69) | PKMGAATSHRTNFCYP11B1 | |
| SCHEMBL2146048 | 0.78 | PKM (0.64) | PKMGAATSHRTNFCYP11B1 | |
| SCHEMBL3831672 | 0.77 | PKM (0.62) | PKMGAATSHRTNFCYP11B1 | |
| SCHEMBL15722800 | 0.77 | POLB (0.56) | PKMGAATSHRTNFCYP11B1 | |
| SCHEMBL29260917 | 0.75 | PKM (0.69) | PKMGAATSHRTNFCYP11B1 | |
| SCHEMBL3264639 | 0.75 | GAA (0.49) | PKMGAATSHRTNFCYP11B1 | |
| SCHEMBL11492795 | 0.75 | PKM (0.76) | PKMGAATSHREGLN1ACP1 | |
| SCHEMBL21314978 | 0.75 | PKM (0.44) | PKMGAATSHRPOLB | |
| SCHEMBL9367365 | 0.74 | PKM (0.59) | PKMGAATSHRTNFCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009847-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, METHOD FOR THE PRODUCTION THEREOF, AND USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-28 | — | — | WO | disclosed |
| EP-2147919-A1 | Heterocyclic substituted amides, method for their manufacture and their use as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2010-01-27 | — | — | EP | disclosed |