SCHEMBL2808649

SCHEMBL2808649

O=C(O)c1ncn(Cc2ccccc2)c1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 1.00
GAA P10253 1/20 1.00
TSHR P16473 1/20 1.00
TNF P01375 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
EGLN1 Q9GZT9 2/20 0.47
HPGD P15428 1/20 0.45
NOTUM Q6P988 1/20 0.44
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
PABPC1 P11940 1/20 0.43
KMT2A Q03164 1/20 0.43
EGLN3 Q9H6Z9 1/20 0.43
PARN O95453 1/20 0.43
CNOT7 Q9UIV1 1/20 0.43
ACP1 P24666 1/20 0.42
KDM4C Q9H3R0 1/20 0.41
ADORA2B P29275 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11495055 0.87 PKM (0.77) PKMGAATSHRCYP11B1CYP11B2
SCHEMBL11492795 0.87 PKM (0.76) PKMGAATSHREGLN1ACP1
SCHEMBL11491981 0.86 PKM (0.75) PKMGAATSHRMEN1TP53
SCHEMBL11484824 0.86 PKM (1.00) PKMGAATSHRCYP11B1CYP11B2
SCHEMBL11492608 0.86 PKM (0.75) PKMGAATSHRCYP11B1CYP11B2
SCHEMBL11484479 0.86 TSHR (0.75) PKMGAATSHRCYP11B1CYP11B2
SCHEMBL11485955 0.86 PKM (0.75) PKMGAATSHRTNFCYP11B1
SCHEMBL11484016 0.85 PKM (0.74) PKMGAATSHRCYP11B1CYP11B2
SCHEMBL4150358 0.85 PKM (0.74) PKMGAATSHRCYP11B1CYP11B2
SCHEMBL11491346 0.84 PKM (0.72) PKMGAATSHRTNFCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118087071-A Preparation method of antibacterial moisture-permeable nylon fiber 南通金余纺塑有限公司 2024-05-28 CN claimed
CN-111944341-A Household environment-friendly coating and preparation method thereof 高雪梅 2020-11-17 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-118087071-A Preparation method of antibacterial moisture-permeable nylon fiber 南通金余纺塑有限公司 2024-05-28 CN disclosed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
CN-111944341-A Household environment-friendly coating and preparation method thereof 高雪梅 2020-11-17 CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 PKM 82/4885GAA 342/4885TSHR 4385/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB PKM 671/4885GAA 874/4885TSHR 4263/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA PKM 215/4885GAA 654/4885TSHR 2885/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA PKM 3571/4885GAA 3205/4885TSHR 3021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.