Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSGALNACT1 | Q8TDX6 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294225 | 0.95 | CSGALNACT1 (0.44) | CSGALNACT1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3227996 | 0.89 | CSGALNACT1 (0.47) | CSGALNACT1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2296373 | 0.83 | CSGALNACT1 (0.51) | CSGALNACT1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2293743 | 0.82 | CSGALNACT1 (0.49) | CSGALNACT1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2297766 | 0.82 | KDM4E (0.43) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2296615 | 0.78 | CSGALNACT1 (0.49) | CSGALNACT1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2296703 | 0.78 | CSGALNACT1 (0.53) | CSGALNACT1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2294779 | 0.78 | MAPT (0.42) | RAB9AMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2298873 | 0.76 | CSGALNACT1 (0.55) | CSGALNACT1 | |
| SCHEMBL2298617 | 0.76 | RAB9A (0.57) | CSGALNACT1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |