Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CSGALNACT1 | Q8TDX6 | 8/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227975 | 0.96 | RAB9A (0.53) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL3237097 | 0.95 | RAB9A (0.52) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2293812 | 0.88 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2297887 | 0.87 | MAPT (0.62) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL2297570 | 0.87 | CSGALNACT1 (0.56) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL2297791 | 0.84 | RAB9A (0.58) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL3231890 | 0.84 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2295109 | 0.81 | MEN1 (0.58) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2295116 | 0.81 | MEN1 (0.58) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2294225 | 0.80 | CSGALNACT1 (0.44) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835428-B2 | Diacylglycerol acyltransferase inhibitors | Piramal Enterprises Limited (IN) | 2014-09-16 | — | — | US | disclosed |
| US-20110196002-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED. | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196002-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | DGAT1, DGAT2, DLAT | RAB9A 3753/4885SMN1; SMN2 4532/4885MEN1 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.