Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234030 | 0.80 | MAPK1 (0.40) | MAPK1KMT2AMEN1HPGDNOTUM | |
| SCHEMBL2170715 | 0.74 | MAPK1 (0.44) | MAPK1KMT2AMEN1TDP1KDM4E | |
| SCHEMBL3233026 | 0.73 | MAPK1 (0.51) | MAPK1KMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL2161013 | 0.72 | MAPK1 (0.52) | MAPK1KMT2AMEN1TDP1POLB | |
| SCHEMBL2315369 | 0.72 | MAPK1 (0.41) | MAPK1KMT2AMEN1TDP1POLB | |
| SCHEMBL2020533 | 0.71 | MEN1 (0.47) | KMT2AMEN1TDP1HPGDPOLB | |
| SCHEMBL1967631 | 0.71 | MEN1 (0.47) | KMT2AMEN1TDP1HPGDPOLB | |
| SCHEMBL3230953 | 0.69 | MAPK1 (0.51) | MAPK1KMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL10418070 | 0.68 | MAPK1 (0.44) | MAPK1KMT2AMEN1TDP1HSP90AA1 | |
| SCHEMBL3240660 | 0.67 | MAPK1 (0.49) | MAPK1KMT2AMEN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029065-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |