Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232134 | 0.80 | MAPK1 (0.41) | MAPK1MAPTHPGDHTTFKBP1A | |
| SCHEMBL3233085 | 0.73 | MAPK1 (0.49) | MAPK1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL10666615 | 0.70 | MAPT (0.55) | MAPK1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL2021950 | 0.70 | MAPT (0.47) | MAPTKMT2AMEN1POLBNPC1 | |
| SCHEMBL1966187 | 0.70 | MAPT (0.47) | MAPTKMT2AMEN1POLBNPC1 | |
| SCHEMBL10509423 | 0.69 | MAPK1 (0.44) | MAPK1MAPTFKBP1AKMT2AMEN1 | |
| SCHEMBL10666518 | 0.69 | MAPT (0.53) | MAPK1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10666511 | 0.69 | MAPT (0.53) | MAPK1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3232029 | 0.68 | MAPK1 (0.46) | MAPK1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10418070 | 0.67 | MAPK1 (0.44) | MAPK1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029065-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |