Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224220 | 1.00 | CHRM3 (0.36) | CHRM3CYP2J2HRH1ALDH1A1KCNH2 | |
| SCHEMBL3226330 | 0.93 | CHRM3 (0.39) | CHRM3ALDH1A1POLBCHRM2CHRM4 | |
| SCHEMBL3226320 | 0.93 | CHRM3 (0.39) | CHRM3ALDH1A1POLBCHRM2CHRM4 | |
| SCHEMBL4741154 | 0.92 | CHRM3 (0.35) | CHRM3CYP2J2ALDH1A1POLBCHRM2 | |
| SCHEMBL4741153 | 0.92 | CHRM3 (0.35) | CHRM3CYP2J2ALDH1A1POLBCHRM2 | |
| SCHEMBL3234490 | 0.89 | CHRM3 (0.35) | CHRM3HRH1ALDH1A1POLBCHRM2 | |
| SCHEMBL3234494 | 0.89 | CHRM3 (0.35) | CHRM3HRH1ALDH1A1POLBCHRM2 | |
| SCHEMBL1109856 | 0.84 | POLB (0.44) | CHRM3ALDH1A1KCNH2POLBCHRM2 | |
| SCHEMBL4786069 | 0.84 | CHRM3 (0.39) | CHRM3ALDH1A1KCNH2POLBCHRM2 | |
| SCHEMBL4786064 | 0.84 | CHRM3 (0.39) | CHRM3ALDH1A1KCNH2POLBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015792-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA-2 RECEPTORS | ARGENTA DISCOVERY LIMITED (GB) | 2010-02-11 | — | — | WO | disclosed |
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |