Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786064 | 1.00 | CHRM3 (0.39) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL1109856 | 0.88 | POLB (0.44) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL3226330 | 0.88 | CHRM3 (0.39) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL3226320 | 0.88 | CHRM3 (0.39) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL1109841 | 0.87 | ALDH1A1 (0.44) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL3221153 | 0.87 | CHRM3 (0.40) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1109823 | 0.87 | CHRM3 (0.40) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1110659 | 0.86 | MEN1 (0.38) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL3232872 | 0.84 | CHRM3 (0.36) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL3224220 | 0.84 | CHRM3 (0.36) | CHRM3POLBCHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |