Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666615 | 0.84 | MAPT (0.55) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL3233026 | 0.80 | MAPK1 (0.51) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL3232029 | 0.79 | MAPK1 (0.46) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL10509423 | 0.78 | MAPK1 (0.44) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL3230953 | 0.76 | MAPK1 (0.51) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL2161013 | 0.74 | MAPK1 (0.52) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL3232108 | 0.74 | MAPK1 (0.40) | MAPK1KDM4EMEN1KMT2AUSP2 | |
| SCHEMBL3234030 | 0.73 | MAPK1 (0.40) | MAPK1L3MBTL1MEN1KMT2AHSD17B10 | |
| SCHEMBL10765806 | 0.73 | MAPK1 (0.50) | MAPK1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL3226317 | 0.73 | MAPK1 (0.38) | MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029065-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |