Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993846 | 0.89 | LMNA (0.50) | SMN1; SMN2TSHRSNCAALDH1A1LMNA | |
| SCHEMBL153280 | 0.89 | LMNA (0.50) | SMN1; SMN2TSHRSNCAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL22806308 | 0.87 | LMNA (0.48) | TSHRSNCAALDH1A1LMNAPOLB | |
| SCHEMBL11296196 | 0.87 | LMNA (0.48) | TSHRSNCAALDH1A1LMNAPOLB | |
| Toluene SCHEMBL5135077 | 0.86 | LMNA (0.50) | SMN1; SMN2TSHRSNCAALDH1A1L3MBTL1 | |
| SCHEMBL13918642 | 0.81 | ALDH1A1 (0.57) | SMN1; SMN2TSHRALDH1A1L3MBTL1LMNA | |
| Toluene SCHEMBL10924679 | 0.81 | TSHR (0.68) | SMN1; SMN2TSHRSNCAALDH1A1L3MBTL1 | |
| SCHEMBL13721233 | 0.81 | GAA (0.52) | TSHRSNCAALDH1A1L3MBTL1LMNA | |
| SCHEMBL12301831 | 0.81 | GAA (0.57) | SMN1; SMN2TSHRALDH1A1L3MBTL1LMNA | |
| SCHEMBL12450093 | 0.80 | LMNA (0.48) | SMN1; SMN2TSHRALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2267040-A1 | CYCLIZED ISOPRENE POLYMER, ALICYCLIC POLYMER AND OPTICAL RESIN | Zeon Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |