SCHEMBL3233897

SCHEMBL3233897

CC1(C(O)C(CCCCOc2ccc(F)cc2F)n2cncn2)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.38
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP19A1 P11511 3/20 0.32
HSP90AB1 P08238 1/20 0.32
GRM2 Q14416 1/20 0.32
MET P08581 2/20 0.32
LMNA P02545 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
ADRA1A P35348 1/20 0.32
CYP51A1 Q16850 1/20 0.32
KCNH2 Q12809 2/20 0.31
TMEM97 Q5BJF2 2/20 0.31
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3237508 0.95 MAPK1 (0.36) MAPK1KMT2AMEN1TDP1CYP19A1
SCHEMBL3240660 0.90 MAPK1 (0.49) MAPK1KMT2AMEN1TDP1GRM2
SCHEMBL3266419 0.86 MAPK1 (0.40) MAPK1KMT2AMEN1TDP1CYP19A1
SCHEMBL3245753 0.86 MAPK1 (0.47) MAPK1KMT2AMEN1TDP1GRM2
SCHEMBL12336846 0.83 MEN1 (0.47) MAPK1KMT2AMEN1TDP1CYP19A1
SCHEMBL3238214 0.82 MAPK1 (0.39) MAPK1GRM2
SCHEMBL3237155 0.82 MAPK1 (0.39) MAPK1KMT2AMEN1TDP1CYP19A1
SCHEMBL10513953 0.80 MAPK1 (0.45) MAPK1KMT2AMEN1TDP1GRM2
SCHEMBL10510759 0.80 MAPK1 (0.45) MAPK1KMT2AMEN1TDP1GRM2
SCHEMBL3238154 0.80 MAPK1 (0.38) MAPK1KMT2AMEN1GRM2MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010029066-A1 IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS BASF SE (DE) 2010-03-18 WO disclosed