Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238214 | 0.95 | MAPK1 (0.39) | MAPK1GRM2DRD2CTSB | |
| SCHEMBL3240660 | 0.92 | MAPK1 (0.49) | MAPK1GRM2DRD2MEN1KMT2A | |
| SCHEMBL3237661 | 0.89 | MAPK1 (0.40) | MAPK1GRM2CTSBMEN1KMT2A | |
| SCHEMBL3245753 | 0.88 | MAPK1 (0.47) | MAPK1GRM2DRD2MEN1KMT2A | |
| SCHEMBL3233897 | 0.86 | MAPK1 (0.38) | MAPK1GRM2MEN1KMT2ACYP19A1 | |
| SCHEMBL2170715 | 0.85 | MAPK1 (0.44) | MAPK1GRM2MEN1KMT2AUSP2 | |
| SCHEMBL10513953 | 0.82 | MAPK1 (0.45) | MAPK1GRM2DRD2MEN1KMT2A | |
| SCHEMBL3237508 | 0.82 | MAPK1 (0.36) | MAPK1GRM2MEN1KMT2ACYP19A1 | |
| SCHEMBL10510759 | 0.82 | MAPK1 (0.45) | MAPK1GRM2DRD2MEN1KMT2A | |
| SCHEMBL3233841 | 0.80 | MAPK1 (0.49) | MAPK1DRD2MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029066-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |