Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.79 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.57 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880368 | 0.88 | S1PR1 (1.00) | S1PR1S1PR5 | |
| SCHEMBL3229139 | 0.84 | S1PR1 (0.72) | S1PR1KMOEGFR | |
| SCHEMBL13216688 | 0.82 | S1PR1 (0.84) | S1PR1 | |
| SCHEMBL3226154 | 0.82 | S1PR1 (0.61) | S1PR1KMOEGFR | |
| SCHEMBL3226915 | 0.79 | S1PR1 (0.61) | S1PR1KMOEGFR | |
| SCHEMBL3227055 | 0.76 | S1PR1 (0.58) | S1PR1KMOEGFR | |
| SCHEMBL3221150 | 0.76 | S1PR1 (0.58) | S1PR1KMOEGFR | |
| SCHEMBL3228067 | 0.75 | EGFR (0.58) | S1PR1KMOEGFR | |
| SCHEMBL3227236 | 0.75 | S1PR1 (0.57) | S1PR1KMOEGFR | |
| SCHEMBL3024966 | 0.75 | S1PR1 (0.61) | S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020432-A8 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA LIMITED (BS) | 2010-03-11 | — | — | WO | claimed |
| WO-2010020432-A2 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2010-02-25 | — | — | WO | claimed |