Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.44 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226154 | 0.88 | S1PR1 (0.61) | S1PR1EGFRERBB3KMONPC1 | |
| SCHEMBL3229082 | 0.88 | KCNH2 (0.59) | S1PR1EGFRERBB3KCNH2KMO | |
| SCHEMBL3225399 | 0.85 | S1PR1 (0.59) | S1PR1KCNH2NPC1RAB9AKMT2A | |
| SCHEMBL3227055 | 0.85 | S1PR1 (0.58) | S1PR1EGFRERBB3KMORAB9A | |
| SCHEMBL3221150 | 0.85 | S1PR1 (0.58) | S1PR1EGFRERBB3KMORAB9A | |
| SCHEMBL3229139 | 0.85 | S1PR1 (0.72) | S1PR1EGFRERBB3KMONPC1 | |
| SCHEMBL3228067 | 0.84 | EGFR (0.58) | S1PR1EGFRERBB3KMONPC1 | |
| SCHEMBL3230524 | 0.83 | KDR (0.54) | S1PR1EGFRERBB3TRPV1NPC1 | |
| SCHEMBL3261684 | 0.82 | SMN1; SMN2 (0.60) | S1PR1EGFRKMT2AKDRSMN1; SMN2 | |
| SCHEMBL3227103 | 0.81 | KMO (0.59) | KCNK9KCNH2KMOTRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020432-A8 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA LIMITED (BS) | 2010-03-11 | — | — | WO | claimed |
| WO-2010020432-A2 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2010-02-25 | — | — | WO | claimed |
| WO-2010020432-A8 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA LIMITED (BS) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010020432-A2 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2010-02-25 | — | — | WO | disclosed |