Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133196 | 0.90 | THRA (0.56) | THRATHRBMGLLPPARALIPG | |
| SCHEMBL1896181 | 0.90 | THRA (0.56) | THRATHRBMGLLPPARALIPG | |
| SCHEMBL2895478 | 0.90 | THRA (0.56) | THRATHRBMGLLPPARALIPG | |
| SCHEMBL15192681 | 0.89 | THRA (0.51) | THRATHRBMGLLPPARALIPG | |
| SCHEMBL5255429 | 0.88 | THRA (0.54) | THRATHRBPPARALIPGLTB4R | |
| Sulfuric Acid SCHEMBL10431395 | 0.85 | THRA (0.52) | THRATHRBMGLLPPARALIPG | |
| Sulfuric Acid SCHEMBL1094888 | 0.85 | THRA (0.52) | THRATHRBMGLLPPARALIPG | |
| Sulfuric Acid SCHEMBL3979284 | 0.85 | THRA (0.52) | THRATHRBMGLLPPARALIPG | |
| Sulfuric Acid SCHEMBL11480869 | 0.85 | THRA (0.52) | THRATHRBMGLLPPARALIPG | |
| Sulfuric Acid SCHEMBL6663311 | 0.85 | THRA (0.52) | THRATHRBMGLLPPARALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1826255-B1 | PUNCTURE SEALING AGENT | BRIDGESTONE CORP (JP) | 2014-05-21 | — | — | EP | disclosed |
| US-7745524-B2 | Puncture sealing agent | BRIDGESTONE CORPORATION (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20080306197-A1 | Puncture Sealing Agent | BRIDGESTONE CORPORATION (JP) | 2008-12-11 | — | — | US | disclosed |
| EP-1826255-A1 | PUNCTURE SEALING AGENT | Bridgestone Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-6156378-A | Process for producing pressure-sensitive adhesive sheet | TOAGOSEI CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |