Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | SHBG | P04278 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236171 | 0.87 | ESR1 (0.69) | ESR1ESR2SHBGSLC6A2CYP3A4 | |
| SCHEMBL3235494 | 0.82 | SHBG (0.48) | ESR1ESR2SHBGKDM4EADRA2A | |
| SCHEMBL3236053 | 0.82 | ESR1 (0.69) | ESR1ESR2SHBGKDM4ESLC6A2 | |
| SCHEMBL3234292 | 0.79 | ESR1 (0.56) | ESR1ESR2KDM4EADRA2ASLC6A2 | |
| SCHEMBL22198693 | 0.78 | SHBG (0.49) | ESR1ESR2SHBGCYP3A4HTT | |
| SCHEMBL984302 | 0.73 | ESR1 (0.74) | ESR1ESR2KDM4ESLC6A2LMNA | |
| SCHEMBL1425068 | 0.72 | ESR1 (0.67) | ESR1ESR2SHBGKDM4EADRA2A | |
| SCHEMBL30320315 | 0.72 | ESR1 (0.61) | ESR1ESR2SHBGKDM4EADRA2A | |
| SCHEMBL3232262 | 0.72 | ESR1 (0.66) | ESR1ESR2SHBGSLC6A2CYP3A4 | |
| SCHEMBL3237146 | 0.71 | ESR1 (0.71) | ESR1ESR2SLC6A2CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |