Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31359497 | 0.84 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1GAAALDH1A1 | |
| SCHEMBL721291 | 0.84 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL14125808 | 0.82 | MAPK1 (0.62) | MAPK1KDM4EL3MBTL1GAAADRA2A | |
| SCHEMBL14740520 | 0.77 | MAPK1 (0.44) | MAPK1KDM4EL3MBTL1CA1CA2 | |
| SCHEMBL2642966 | 0.77 | PIP5K1C (0.49) | KDM4EPTGS1ALDH1A1PARP1HIF1A | |
| SCHEMBL30556510 | 0.76 | GABRG2 (0.46) | MAPK1ALDH1A1PDK2 | |
| SCHEMBL754777 | 0.76 | CYP1A2 (0.56) | MAPK1KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL15956221 | 0.76 | GABRG2 (0.46) | MAPK1ALDH1A1PDK2 | |
| SCHEMBL7942053 | 0.74 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1GAAHIF1A | |
| SCHEMBL30753596 | 0.74 | ALDH1A1 (0.47) | MAPK1KDM4EL3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010189-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |