SCHEMBL3236808

SCHEMBL3236808

Cc1[c]ccc(C(C)(C)C)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.48
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
ALDH1A1 P00352 5/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
TYR P14679 2/20 0.41
POLB P06746 1/20 0.41
CA1 P00915 2/20 0.38
CYP2C9 P11712 4/20 0.38
CYP2C19 P33261 3/20 0.38
CYP1A2 P05177 2/20 0.38
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 1/20 0.37
ALOX15 P16050 3/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ATP2A2 P16615 1/20 0.36
ATP2A3 Q93084 1/20 0.36
ALOX12 P18054 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9158392 0.78 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1SMN1; SMN2
SCHEMBL5606445 0.76 NR1I2 (0.31) CA2GABRA1GABRB2ALDH1A1TYR
SCHEMBL11568827 0.74
SCHEMBL2353186 0.72
SCHEMBL4438400 0.72
SCHEMBL47580 0.70 CA2 (0.68) CA2GABRA1GABRB2ALDH1A1SMN1; SMN2
SCHEMBL30938109 0.70 CA2 (0.68) CA2GABRA1GABRB2ALDH1A1SMN1; SMN2
SCHEMBL2541721 0.70 CA2 (0.38) CA2GABRA1GABRB2ALDH1A1SMN1; SMN2
SCHEMBL10670576 0.70 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2TYRCYP2C9CYP1A2
SCHEMBL23004 0.68 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1549704-A1 STABILIZED POLYMER COMPOSITION Borealis Technology Oy (FI) 2005-07-06 EP claimed
WO-2004033545-A1 STABILIZED POLYMER COMPOSITION BOREALIS TECHNOLOGY OY (FI) 2004-04-22 WO claimed
US-9856914-B2 Joint bearing lubricant system THE BOEING COMPANY (US) 2018-01-02 US disclosed
EP-2813719-B1 Joint bearing lubricant system BOEING CO (US) 2017-06-14 EP disclosed
US-20150369285-A1 JOINT BEARING LUBRICANT SYSTEM THE BOEING COMPANY 2015-12-24 US disclosed
US-9140302-B2 Joint bearing lubricant system THE BOEING COMPANY (US) 2015-09-22 US disclosed
US-20140369634-A1 JOINT BEARING LUBRICANT SYSTEM THE BOEING COMPANY 2014-12-18 US disclosed
EP-2813719-A1 Joint bearing lubricant system The Boeing Company (US) 2014-12-17 EP disclosed
EP-1625193-B1 BORATE ESTER LUBRICANT ADDITIVES BASF SE (DE) 2010-07-28 EP disclosed
US-7291581-B2 Borate ester lubricant additives CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-11-06 US disclosed
EP-1625193-A1 BORATE ESTER LUBRICANT ADDITIVES Ciba SC Holding AG (CH) 2006-02-15 EP disclosed
WO-2004104146-A1 BORATE ESTER LUBRICANT ADDITIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-02 WO disclosed
US-20040235681-A1 Borate ester lubricant additives CIBA SPECIALTY CHEMICALS CORP. 2004-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235681-A1 Borate ester lubricant additives GRK1, BRSK1, EBPL CA2 3326/4885GABRA1 534/4885GABRB2 763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.