Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429153 | 0.84 | MEN1 (0.49) | MAPTMEN1KMT2APPARACYP1A2 | |
| SCHEMBL20133460 | 0.82 | PPARA (0.46) | MAPTMEN1KMT2APPARACYP1A2 | |
| SCHEMBL30901955 | 0.82 | CNR1 (0.47) | MAPTMEN1KMT2APPARACYP1A2 | |
| SCHEMBL1811683 | 0.80 | KMT2A (0.54) | MAPTMEN1KMT2ANPSR1PPARA | |
| SCHEMBL1811163 | 0.79 | PPARA (0.67) | MAPTMEN1KMT2ANPSR1PPARA | |
| SCHEMBL15912487 | 0.79 | KMT2A (0.48) | MAPTMEN1KMT2ANPSR1PPARA | |
| SCHEMBL3233909 | 0.78 | KMT2A (0.47) | MAPTMEN1KMT2ANPSR1PPARA | |
| SCHEMBL3573347 | 0.78 | PPARA (0.50) | MAPTMEN1KMT2ANPSR1PPARA | |
| SCHEMBL12438632 | 0.78 | MAPT (0.44) | MAPTMEN1KMT2ANPSR1PPARA | |
| SCHEMBL19696240 | 0.77 | CYP3A4 (0.50) | MAPTMEN1KMT2APPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010184-A1 | [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |