Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417538 | 0.84 | ALDH1A1 (0.49) | CNR1PPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4429153 | 0.84 | MEN1 (0.49) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL3237160 | 0.82 | MAPT (0.50) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL20133460 | 0.82 | PPARA (0.46) | CNR1PPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21991451 | 0.80 | PPARA (0.46) | CNR1PPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3158911 | 0.79 | PPARA (0.67) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL11550869 | 0.78 | PPARA (0.50) | CNR1PPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4688589 | 0.78 | PPARA (0.48) | CNR1PPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24542744 | 0.78 | CYP1A2 (0.53) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL19696240 | 0.77 | CYP3A4 (0.50) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARMACEUTICALS INC. | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | GPR88, GPR65, GPR68 | CNR1 102/4885PPARA 355/4885CYP1A2 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.