Sugi Predict

Sugi Predict / Compounds / SCHEMBL323823

SCHEMBL323823

SCHEMBL323823

O=C(O)C1CC1c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 5/20 0.70
▸ HDAC4 P56524 1/20 0.66
▸ ALDH1A1 P00352 2/20 0.63
▸ SLC9A1 P19634 1/20 0.59
▸ HPGD P15428 1/20 0.56
▸ DEGS1 O15121 1/20 0.54
▸ NAMPT P43490 1/20 0.53
▸ SIGMAR1 Q99720 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ GAA P10253 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ AKR1C3 P42330 1/20 0.52
▸ AKR1C1 Q04828 1/20 0.52
▸ HRH3 Q9Y5N1 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL323824 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL5315326 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL1172743 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL3359435 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL2034678 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL8295172 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL5217474 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL4126470 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
Hydrochloric Acid SCHEMBL5089207 0.98 FFAR1 (0.68) FFAR1HDAC4ALDH1A1SLC9A1HPGD
Hydrochloric Acid SCHEMBL5089203 0.98 FFAR1 (0.68) FFAR1HDAC4ALDH1A1SLC9A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290491-A Copper nanocluster and preparation method thereof 清华大学 2024-07-05 — — CN claimed
CN-105819380-B A kind of yellow peach carrot compound fruit vinegar raw material apparatus for automatically lifting and its method of work 徐州工程学院 2018-02-06 — — CN claimed
EP-2742029-B1 N-(BENZIMIMDAZOL-2-YL)-CYCLOPROPANE CARBOXAMIDES AS LYSOPHOSPHATIDIC ACID ANTAGONISTS MERCK PATENT GMBH (DE) 2016-10-05 — — EP claimed
CN-103702984-B As N-(benzimidazolyl-2 radicals-yl)-cyclopropane carboxamide class of lysophosphatide acid antagonist MERCK PATENT GMBH (DE) 2016-05-11 — — CN claimed
US-9199920-B2 Antiviral drugs for treatment of arenavirus infection Kineta Four, LLC (US) 2015-12-01 — — US claimed
US-8912202-B2 N-(benzimimdazol-2-yl)-cyclopropane carboxamides as lysophosphatidic acid antagonists MERCK PATENT GMBH (DE) 2014-12-16 — — US claimed
US-8906866-B2 Antibiotic compositions for the treatment of gram negative infections BIOSOURCE PHARM, INC. (US) 2014-12-09 — — US claimed
US-20140228378-A1 N-(Benzimimdazol-2-yl)-Cyclopropane Carboxamides as Lysophosphatidic Acid Antagonists MERCK PATENT GMBH (DE) 2014-08-14 — — US claimed
EP-2742029-A1 N-(BENZIMIMDAZOL-2-YL)-CYCLOPROPANE CARBOXAMIDES AS LYSOPHOSPHATIDIC ACID ANTAGONISTS Merck Patent GmbH (DE) 2014-06-18 — — EP claimed
CN-103702984-A N-(benzimimdazol-2-yl)-cyclopropane carboxamides as lysophosphatidic acid antagonists MERCK PATENT GMBH 2014-04-02 — — CN claimed
US-20030216390-A1 Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues NEUROGEN CORPORATION 2003-11-20 — — US claimed
EP-1313710-A1 PYRAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS Pfizer Products Inc. (US) 2003-05-28 — — EP claimed
US-20020103185-A1 Pyrazole derivatives PFIZER PRODUCTS INC. 2002-08-01 — — US claimed
WO-2002018346-A1 PYRAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS PFIZER PRODUCTS INC. (US) 2002-03-07 — — WO claimed
EP-1019367-A1 DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-07-19 — — EP claimed
CN-1047591-C N-substituted carbonyloxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AERICAN CYANAMID CO (US) 1999-12-22 — — CN claimed
WO-1999007672-A1 DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1999-02-18 — — WO claimed
EP-0594941-B1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 — — EP claimed
CN-1087082-A N-substituted carbonyloxyalkylpyrrinsecticidal insecticidal, miticide and invertebrate poison AMERICAN CYANAMID CO (US) 1994-05-25 — — CN claimed
US-4016204-A ISOMERIZING ETHYL-2-PHENYL-CYCLOPROPANE CARBOXYLATE NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-05 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228378-A1 N-(Benzimimdazol-2-yl)-Cyclopropane Carboxamides as Lysophosphatidic Acid Antagonists LPAR5, LPAR2, LPAR1 FFAR1 85/4885HDAC4 1534/4885ALDH1A1 1766/4885
US-20030216390-A1 Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues MCHR1, MCHR2, MC1R FFAR1 264/4885HDAC4 2021/4885ALDH1A1 1474/4885
US-20020103185-A1 Pyrazole derivatives CDK1, CDK5, CDK3 FFAR1 1181/4885HDAC4 778/4885ALDH1A1 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.