SCHEMBL323824

SCHEMBL323824

O=C(O)[C@@H]1C[C@H]1c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.70
HDAC4 P56524 1/20 0.66
ALDH1A1 P00352 2/20 0.63
SLC9A1 P19634 1/20 0.59
HPGD P15428 1/20 0.56
DEGS1 O15121 1/20 0.54
NAMPT P43490 1/20 0.53
SIGMAR1 Q99720 1/20 0.53
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
AKR1C3 P42330 1/20 0.52
AKR1C1 Q04828 1/20 0.52
HRH3 Q9Y5N1 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5315326 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL1172743 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL3359435 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL2034678 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL8295172 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL5217474 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL323823 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL4126470 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
Hydrochloric Acid SCHEMBL5089207 0.98 FFAR1 (0.68) FFAR1HDAC4ALDH1A1SLC9A1HPGD
Hydrochloric Acid SCHEMBL5089203 0.98 FFAR1 (0.68) FFAR1HDAC4ALDH1A1SLC9A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707872-A Method for amidation of carboxylic acid and continuous flow photochemistry device 国网安徽省电力有限公司电力科学研究院 2025-03-28 CN claimed
CN-119504653-A Carboxylic acid amidation method 国网安徽省电力有限公司电力科学研究院 2025-02-25 CN claimed
CN-119504652-A Method for amidating carboxylic acid and gas-liquid mixed flow photochemical device 国网安徽省电力有限公司电力科学研究院 2025-02-25 CN claimed
US-8906866-B2 Antibiotic compositions for the treatment of gram negative infections BIOSOURCE PHARM, INC. (US) 2014-12-09 US claimed
US-20110003867-A1 NOVEL 2-ETHYL-METHYL-AMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS NEUROSEARCH A/S (DK) 2011-01-06 US claimed
EP-2231610-A1 NOVEL 2-DIMETHYLAMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS NeuroSearch A/S (DK) 2010-09-29 EP claimed
EP-2231609-A1 NOVEL 2-ETHYL-METHYL-AMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS NeuroSearch A/S (DK) 2010-09-29 EP claimed
EP-2231608-A1 NOVEL 2-DIETHYLAMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS NeuroSearch A/S (DK) 2010-09-29 EP claimed
EP-1836163-B1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN NOVARTIS AG (CH) 2010-09-22 EP claimed
US-20100087427-A1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN BREITENSTEIN WERNER 2010-04-08 US claimed
US-7317025-B2 Non-peptidic NPY Y2 receptor inhibitors JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, LLC (US) 2008-01-08 US claimed
EP-1761542-B1 OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS HOFFMANN LA ROCHE (CH) 2008-01-02 EP claimed
EP-1836163-A2 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN Novartis AG (CH) 2007-09-26 EP claimed
WO-2006066896-A2 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN NOVARTIS AG (CH) 2006-06-29 WO claimed
US-20060036098-A1 Carbonylamino-benzimidazole derivatives as androgen receptor modulators MERCK SHARP & DOHME CORP. 2006-02-16 US claimed
EP-1585749-A1 DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS PFIZER INC. (US) 2005-10-19 EP claimed
US-20050070534-A1 Non-peptidic NPY Y2 receptor inhibitors JANSSEN PHARMACEUTICA, N.V. (BE) 2005-03-31 US claimed
CN-1521164-A Pyran isoflavone molluscacide synthesizing method and formulation 中国人民解放军南京军区联勤部军事医 2004-08-18 CN claimed
WO-2004063198-A1 DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS PFIZER INC. (US) 2004-07-29 WO claimed
US-4016204-A ISOMERIZING ETHYL-2-PHENYL-CYCLOPROPANE CARBOXYLATE NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087427-A1 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN REN, ACE, PEPD FFAR1 4600/4885HDAC4 3345/4885ALDH1A1 494/4885
US-20060036098-A1 Carbonylamino-benzimidazole derivatives as androgen receptor modulators AR, SHBG, BRCA1 FFAR1 110/4885HDAC4 163/4885ALDH1A1 916/4885
US-20110003867-A1 NOVEL 2-ETHYL-METHYL-AMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS KCNA7, KCNN3, KCNJ2 FFAR1 2462/4885HDAC4 2029/4885ALDH1A1 3829/4885
US-20050070534-A1 Non-peptidic NPY Y2 receptor inhibitors NPY2R, NPY1R, NPY5R FFAR1 434/4885HDAC4 1495/4885ALDH1A1 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.