SCHEMBL4126470

SCHEMBL4126470

O=C(O)[C@@H]1C[C@@H]1c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.70
HDAC4 P56524 1/20 0.66
ALDH1A1 P00352 2/20 0.63
SLC9A1 P19634 1/20 0.59
HPGD P15428 1/20 0.56
DEGS1 O15121 1/20 0.54
NAMPT P43490 1/20 0.53
SIGMAR1 Q99720 1/20 0.53
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
AKR1C3 P42330 1/20 0.52
AKR1C1 Q04828 1/20 0.52
HRH3 Q9Y5N1 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL323824 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL5315326 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL1172743 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL3359435 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL2034678 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL8295172 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL5217474 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
SCHEMBL323823 1.00 FFAR1 (0.70) FFAR1HDAC4ALDH1A1SLC9A1HPGD
Hydrochloric Acid SCHEMBL5089207 0.98 FFAR1 (0.68) FFAR1HDAC4ALDH1A1SLC9A1HPGD
Hydrochloric Acid SCHEMBL5089203 0.98 FFAR1 (0.68) FFAR1HDAC4ALDH1A1SLC9A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4016204-A ISOMERIZING ETHYL-2-PHENYL-CYCLOPROPANE CARBOXYLATE NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-05 US claimed
US-12466805-B2 Pharmaceutical compounds ALMAC DISCOVERY LIMITED (GB) 2025-11-11 US disclosed
WO-2025215536-A1 MACROCYCLIC PANRAS INHIBITORS FOR THE TREATMENT OF CANCER NOVARTIS AG (CH) 2025-10-16 WO disclosed
EP-4617264-A1 ISOINDOLINONE DERIVATIVE HAVING ARYLCYCLOALKYLAMIDE STRUCTURE, AND USE THEREOF Oncord Bio Inc (KR) 2025-09-17 EP disclosed
CN-112867705-B Opioid receptor modulators and products and methods related thereto 埃皮欧黛公司 2024-08-20 CN disclosed
EP-3774722-B1 OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO EPIODYNE INC (US) 2024-07-24 EP disclosed
US-20240174662-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES CILAG AG (CH) 2024-05-30 US disclosed
WO-2024101763-A1 ISOINDOLINONE DERIVATIVE HAVING ARYLCYCLOALKYLAMIDE STRUCTURE, AND USE THEREOF 주식회사 온코드바이오 2024-05-16 WO disclosed
EP-4284802-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES Janssen Biotech, Inc. (US) 2023-12-06 EP disclosed
WO-2023125846-A1 COMPOUND FOR PREVENTING AND TREATING CORONAVIRUS INFECTION, CONJUGATE THEREOF AND METHOD THEREFOR 苏州爱科百发生物医药技术有限公司 2023-07-06 WO disclosed
US-7323478-B2 Melanin concentrating hormone receptor ligands NEUROGEN CORPORATION (US) 2008-01-29 US disclosed
US-7323478-B2 Melanin concentrating hormone receptor ligands NEUROGEN CORPORATION (US) 2008-01-29 US disclosed
US-20070037816-A1 Bicyclic piperazines as metabotropic glutatmate receptor antagonists ASTRAZENECA AB (SE) 2007-02-15 US disclosed
US-20070037816-A1 Bicyclic piperazines as metabotropic glutatmate receptor antagonists ASTRAZENECA AB (SE) 2007-02-15 US disclosed
EP-0436199-B1 Cyclopropyl derivative lipoxygenase inhibitors ABBOTT LAB (US) 1994-08-03 EP disclosed
WO-1992020665-A1 THIAZOLIDINE DERIVATIVES AND THEIR USE IN THERAPY GLAXO GROUP LIMITED (GB) 1992-11-26 WO disclosed
US-5120752-A N-(1-(20(3-pyridyloxy)phenyl)cyclopropyl) alkyl-N-hydroxyurea compounds, antiinflammatory agents ABBOTT LABORATORIES (US) 1992-06-09 US disclosed
US-5037853-A Antiinflammatory agents ABBOTT LABORATORIES (US) 1991-08-06 US disclosed
EP-0436199-A1 Cyclopropyl derivative lipoxygenase inhibitors ABBOTT LABORATORIES (US) 1991-07-10 EP disclosed
US-4016204-A ISOMERIZING ETHYL-2-PHENYL-CYCLOPROPANE CARBOXYLATE NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466805-B2 Pharmaceutical compounds USP19, USP18, UBE2I FFAR1 4027/4885HDAC4 819/4885ALDH1A1 621/4885
US-20240174662-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES SIK2, SIK1, SGK2 FFAR1 3769/4885HDAC4 745/4885ALDH1A1 4411/4885
US-20070037816-A1 Bicyclic piperazines as metabotropic glutatmate receptor antagonists GRM5, GRM1, GRIN1 FFAR1 74/4885HDAC4 1082/4885ALDH1A1 769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.