Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.74 |
| ▸ | ACHE | P22303 | 4/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | ALPL | P05186 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ALPI | P09923 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | ALPG | P10696 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909991 | 0.99 | ELANE (0.75) | ELANEACHEPTGS2ALOX5KDM4E | |
| SCHEMBL3231721 | 0.91 | ABCG2 (0.78) | ELANEACHEPTGS2ALOX5MEN1 | |
| SCHEMBL3245112 | 0.89 | ABCG2 (0.76) | ELANEACHEPTGS2ALOX5ABCG2 | |
| SCHEMBL16105743 | 0.86 | ELANE (0.98) | ELANEACHEPTGS2ALOX5MAPT | |
| SCHEMBL12909498 | 0.86 | ELANE (0.98) | ELANEACHEPTGS2ALOX5MAPT | |
| SCHEMBL3238475 | 0.86 | ELANE (0.98) | ELANEACHEPTGS2ALOX5MAPT | |
| Nymphaeol A SCHEMBL16105856 | 0.85 | ELANE (1.00) | ELANEACHEPTGS2ALOX5MAPT | |
| Nymphaeol A SCHEMBL30637584 | 0.85 | ELANE (1.00) | ELANEACHEPTGS2ALOX5MAPT | |
| Nymphaeol A SCHEMBL7795014 | 0.85 | ELANE (1.00) | ELANEACHEPTGS2ALOX5MAPT | |
| Nymphaeol A SCHEMBL909992 | 0.85 | ELANE (1.00) | ELANEACHEPTGS2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110054014-A1 | PRENYLFLAVANONE COMPOUNDS AND USES THEREOF | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2011-03-03 | — | — | US | disclosed |
| US-20100144857-A1 | PRENYLFLAVANONE COMPOUNDS AND USES THEREOF | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144857-A1 | PRENYLFLAVANONE COMPOUNDS AND USES THEREOF | FNTA, CYP4F2, CYP4F3 | ELANE 1512/4885ACHE 3450/4885PTGS2 599/4885 |
| US-20110054014-A1 | PRENYLFLAVANONE COMPOUNDS AND USES THEREOF | FNTA, CYP4F2, CYP4F3 | ELANE 1512/4885ACHE 3450/4885PTGS2 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.