Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 1.00 |
| ▸ | ACHE | P22303 | 4/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 4/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.84 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.84 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.72 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.69 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nymphaeol A SCHEMBL16105856 | 1.00 | ELANE (1.00) | ELANEACHEPTGS2ALOX5TP53 | |
| Nymphaeol A SCHEMBL909988 | 1.00 | ELANE (1.00) | ELANEACHEPTGS2ALOX5TP53 | |
| Nymphaeol A SCHEMBL30637584 | 1.00 | ELANE (1.00) | ELANEACHEPTGS2ALOX5TP53 | |
| Nymphaeol A SCHEMBL7795014 | 1.00 | ELANE (1.00) | ELANEACHEPTGS2ALOX5TP53 | |
| Nymphaeol A SCHEMBL30532526 | 1.00 | ELANE (1.00) | ELANEACHEPTGS2ALOX5TP53 | |
| SCHEMBL16105743 | 0.99 | ELANE (0.98) | ELANEACHEPTGS2ALOX5TP53 | |
| SCHEMBL3238475 | 0.99 | ELANE (0.98) | ELANEACHEPTGS2ALOX5TP53 | |
| SCHEMBL12909498 | 0.99 | ELANE (0.98) | ELANEACHEPTGS2ALOX5TP53 | |
| SCHEMBL26621041 | 0.93 | ELANE (0.86) | ELANEACHEPTGS2ALOX5TP53 | |
| SCHEMBL13043321 | 0.93 | ELANE (0.86) | ELANEACHEPTGS2ALOX5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2783684-B1 | PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES | NATUREWISE BIOTECH & MEDICALS CORP (TW) | 2018-10-03 | — | — | EP | claimed |
| US-9457007-B2 | Prenylflavanone compounds for modulating diabetes | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2016-10-04 | — | — | US | claimed |
| US-20140296543-A1 | PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2014-10-02 | — | — | US | claimed |
| EP-2783684-A1 | Prenylflavanone compounds for modulating diabetes | NatureWise Biotech & Medicals Corporation (TW) | 2014-10-01 | — | — | EP | claimed |
| CN-101883574-B | Periodontal bacterial growth inhibitor, oral hygiene product, and food and drink | POKKA CORP | 2013-06-26 | — | — | CN | claimed |
| EP-2783684-B1 | PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES | NATUREWISE BIOTECH & MEDICALS CORP (TW) | 2018-10-03 | — | — | EP | disclosed |
| US-9457007-B2 | Prenylflavanone compounds for modulating diabetes | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2016-10-04 | — | — | US | disclosed |
| US-20140296543-A1 | PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2014-10-02 | — | — | US | disclosed |
| EP-2783684-A1 | Prenylflavanone compounds for modulating diabetes | NatureWise Biotech & Medicals Corporation (TW) | 2014-10-01 | — | — | EP | disclosed |
| CN-101883574-B | Periodontal bacterial growth inhibitor, oral hygiene product, and food and drink | POKKA CORP | 2013-06-26 | — | — | CN | disclosed |
| US-20130122121-A1 | METHOD OF USE OF AN ANTI-METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AGENT AND AN ANTI-VANCOMYCIN-RESISTANT ENTEROCOCCUS AGENT | POKKA CORPORATION (JP) | 2013-05-16 | — | — | US | disclosed |
| US-20130115175-A1 | Periodontal Bacterial Growth Inhibitor, Oral Hygiene Product, and Food and Drink | POKKA CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| US-7829591-B2 | Flavanone compound and uses thereof | POKKA CORPORATION (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20100247455-A1 | Periodontal Bacterial Growth Inhibitor, Oral Hygiene Product, and Food and Drink | POKKA CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2216037-A1 | PERIODONTAL BACTERIAL GROWTH INHIBITOR, ORAL HYGIENE PRODUCT, AND FOOD AND DRINK | POKKA CORPORATION (JP) | 2010-08-11 | — | — | EP | disclosed |
| EP-2186806-A1 | Flavanone compound and uses thereof | POKKA CORPORATION (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-7256214-B2 | 5,7,3',4'-Tetrahydroxy-5'-C-geranylflavanone (isonymphaeol-B), isolated from an Okinawa propolis; microbiocide, antitumor agent, food, beverage and cosmetic preservative; antioxidant food supplement | POKKA CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| US-20070161579-A1 | FLAVANONE COMPOUND AND USES THEREOF | POKKA CORPORATION (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20060292204-A1 | Flavanone compound and uses thereof | POKKA CORPORATION (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1640371-A1 | FLAVANONE COMPOUND AND USES THEREOF | POKKA CORPORATION (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296543-A1 | PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES | SREBF2, GID4, SREBF1 | ELANE 3443/4885ACHE 4566/4885PTGS2 559/4885 |
| US-20070161579-A1 | FLAVANONE COMPOUND AND USES THEREOF | NQO1, GPX4, NDUFV2 | ELANE 501/4885ACHE 565/4885PTGS2 2072/4885 |
| US-20060292204-A1 | Flavanone compound and uses thereof | NQO1, GPX4, NDUFV2 | ELANE 501/4885ACHE 565/4885PTGS2 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.