Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TEK | Q02763 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CTSC | P53634 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | BMX | P51813 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246389 | 0.89 | CTSC (0.58) | KDM4EGAATEKKDRALDH1A1 | |
| SCHEMBL3237832 | 0.86 | MAPT (0.53) | KDM4EGAATEKKDRALDH1A1 | |
| SCHEMBL3243306 | 0.82 | CTSC (0.70) | KDM4EGAATEKKDRALDH1A1 | |
| SCHEMBL3246808 | 0.81 | CTSC (0.64) | KDM4EGAATEKKDRALDH1A1 | |
| SCHEMBL3243096 | 0.81 | CTSC (0.61) | KDM4EGAATEKKDRALDH1A1 | |
| SCHEMBL3243019 | 0.81 | LCK (0.55) | KDM4EGAATEKKDRALDH1A1 | |
| SCHEMBL2883710 | 0.79 | MAPT (0.68) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3235336 | 0.78 | CTSC (0.59) | KDM4EGAAALDH1A1POLBHPGD | |
| SCHEMBL3246053 | 0.77 | CTSC (0.62) | KDM4EGAATEKKDRALDH1A1 | |
| SCHEMBL3247802 | 0.75 | BRAF (0.58) | KDM4EKDRMEN1KMT2ACTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |