Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 10/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 2/20 | 0.55 |
| ▸ | IDH2 | P48735 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | TEK | Q02763 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243096 | 0.93 | CTSC (0.61) | CTSCKDM4EGAAMAPTMEN1 | |
| SCHEMBL3235336 | 0.87 | CTSC (0.59) | CTSCKDM4EGAAMAPTMEN1 | |
| SCHEMBL3246053 | 0.84 | CTSC (0.62) | CTSCKDM4EGAAMAPTMEN1 | |
| SCHEMBL25658138 | 0.83 | CTSC (1.00) | CTSC | |
| SCHEMBL29816660 | 0.83 | CTSC (1.00) | CTSC | |
| SCHEMBL3246808 | 0.83 | CTSC (0.64) | CTSCKDM4EGAAMAPTMEN1 | |
| SCHEMBL3246389 | 0.82 | CTSC (0.58) | CTSCKDM4EGAAMAPTMEN1 | |
| SCHEMBL3239206 | 0.82 | KDM4E (0.56) | CTSCKDM4EGAAMAPTMEN1 | |
| SCHEMBL31593020 | 0.81 | DGAT1 (0.66) | CTSCKDR | |
| SCHEMBL3242738 | 0.80 | KDM4E (0.54) | CTSCKDM4EGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |